Pentameric protein

5 proteins come together to form a channel. Each channel consist of two alpha, one beta, one gamma and one delta chains. These 5 chains assemble together (along with certain receptors like protons or Acetyl-choline) forming the structure of the channel. The ligand-gated channel on the post-synaptic junction of the muscle-end plate is an example of such a channel. They are acetyl choline operated ion channels, which means that acetyl choline brings about a conformational change. The channel allows the free movement of the cations like Na and K when acetyl choline binds to its receptors.