H1FOO

Histone H1oo is a is_associated_with::protein that in humans is encoded by the H1FOO is_associated_with::gene.

Function
is_associated_with::Histones are basic nuclear proteins that are responsible for the is_associated_with::nucleosome structure of the chromosomal fiber in is_associated_with::eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes.

It incorporates into sperm chromatin after is_associated_with::fertilisation.