N-acetyltransferase 1

N-acetyltransferase 1 (arylamine N-acetyltransferase) is a is_associated_with::protein that in humans is encoded by the NAT1 is_associated_with::gene.

This gene is one of two arylamine is_associated_with::N-acetyltransferase (NAT) genes in the is_associated_with::human genome, and is orthologous to the mouse and rat NAT2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from is_associated_with::acetyl-CoA to various arylamine and is_associated_with::hydrazine substrates. This enzyme helps metabolize drugs and other is_associated_with::xenobiotics, and functions in folate is_associated_with::catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].