Rs62623713

In an exome sequencing study of 1425 morbidly obese and 782 individuals non-synonymous rare G variant of Rs62623713 in SYPL2 was found associated with body mass index (beta=2.13 (1.09, 3.18), P=6.28 &#215; 10&#8722;5) and odds ratio of 1.32 for obesity.

Exome sequencing followed by genotyping suggests SYPL2 as a susceptibility gene for morbid obesity