GUCY2F

Retinal guanylyl cyclase 2 also known as guanylate cyclase F (GUCY2F) is a is_associated_with::protein that in humans is encoded by the GUCY2F is_associated_with::gene.

Function
The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the is_associated_with::retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual is_associated_with::signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein.

Clinical significance
Defects in this gene may be a cause of X-linked is_associated_with::retinitis pigmentosa.