C14orf104

Chromosome 14 open reading frame 104, also known as kintoun, is a is_associated_with::protein that in humans is encode by the KTU is_associated_with::gene. The now official name is DNAAF2

Function
Kintoun is a highly conserved protein involved in the preassembly of is_associated_with::dynein arm complexes which power is_associated_with::cilia. These complexes are found in some cilia and are assembled in the is_associated_with::cytoplasm prior to transport for is_associated_with::ciliogenesis.<ref name="entrez"/

Clinical significance
Mutations in the C14orf104 are associated with is_associated_with::primary ciliary dyskinesia.