Rs137854604

A publication has reported that the minor (and quite rare) T allele of rs137854604 was seen in a 39-year-old Japanese patient who was admitted to the hospital for recurrent syncope and suffered an episode of spontaneous ventricular fibrillation while hospitalized. The patient did not have typical ECG findings of Brugada syndrome.

This variant meets the criteria published in 2013 by the ACMG regarding incidental findings in exome or genome sequencing, as a variant that they do recommend informing a patient about.