FANCG

Fanconi anemia group G protein is a is_associated_with::protein that in humans is encoded by the FANCG is_associated_with::gene.

Function
FANCG, involved in is_associated_with::Fanconi anemia, confers resistance to both is_associated_with::hygromycin B and is_associated_with::mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a is_associated_with::leucine-zipper motif at its is_associated_with::N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified. The FANCG gene is responsible for complementation group G.

Interactions
FANCG has been shown to interact with is_associated_with::FANCF,

is_associated_with::FANCA,                is_associated_with::FANCE  and is_associated_with::BRCA2.