Rs2241712

rs2241712, a SNP in the promoter region of the transforming growth factor beta1 TGFB1 gene has been associated with increased risk for chronic obstructive pulmonary disease (COPD). Although smoking is the main risk factor, smokers with a rs2241712(A) allele (or 2 other TGFB1 SNPs, rs1982073 and rs1800469) were more likely to develop COPD, based on a study of ~700 Caucasian subjects

asthma rs2241712(A) and rs1800469(C) associated with increased airway responsiveness


 * is_associated_with_disease::Asthma
 * is_associated_with_disease::Chronic obstructive pulmonary disease