T-complex 1

T-complex protein 1 subunit alpha is a is_associated_with::protein that in humans is encoded by the TCP1 is_associated_with::gene.

Function
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.

Interactions
T-complex 1 has been shown to interact with is_associated_with::PPP4C and is_associated_with::HDAC3.