PDE4D

cAMP-specific 3',5'-cyclic phosphodiesterase 4D is an is_associated_with::enzyme that in humans is encoded by the PDE4D is_associated_with::gene.

Interactions
PDE4D has been shown to interact with is_associated_with::myomegalin and is_associated_with::GNB2L1.

Clinical relevance
Mutations in this gene have been associated to cases of is_associated_with::acrodysostosis.

This is the subtype of PDE4 that appears to be involved in the is_associated_with::emetic and is_associated_with::antidepressant effects of is_associated_with::PDE4 inhibitors.