MT-ATP8

ATP synthase protein 8 is an is_associated_with::protein that in humans is encoded by the MT-ATP8 is_associated_with::gene. It is a subunit of mitochondrial ATP synthase.

This subunit appears to be an integral component of the stator stalk in yeast is_associated_with::mitochondrial is_associated_with::F-ATPases. The stator stalk is anchored in the is_associated_with::membrane, and acts to prevent futile rotation of the ATPase subunits relative to the rotor during coupled ATP synthesis/hydrolysis. This subunit may have an analogous function in is_associated_with::Metazoa. Subunit 8 differs in sequence between Metazoa, is_associated_with::plants and fungi).