CLK1

Dual specificity protein kinase CLK1 is an is_associated_with::enzyme that in humans is encoded by the CLK1 is_associated_with::gene.

Function
This gene encodes a member of the CDC2-like (or LAMMER) family of is_associated_with::dual specificity protein kinases. In the is_associated_with::cell nucleus, the encoded protein phosphorylates is_associated_with::serine/is_associated_with::arginine-rich proteins involved in pre-mRNA processing, releasing them into the is_associated_with::nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine-rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection.

Interactions
CLK1 has been shown to interact with is_associated_with::ASF/SF2.