Angiomotin-like protein 1

Angiomotin-like protein 1 is a is_associated_with::protein that in humans is encoded by the AMOTL1 is_associated_with::gene.

Function
The protein encoded by this gene is a is_associated_with::peripheral membrane protein that is a component of is_associated_with::tight junctions or TJs. TJs form an apical junctional structure and act to control is_associated_with::paracellular permeability and maintain is_associated_with::cell polarity. This protein is related to is_associated_with::angiomotin, an angiostatin binding protein that regulates is_associated_with::endothelial cell migration and is_associated_with::capillary formation.