Aminotransferase, class V

Aminotransferase class-V  is an evolutionary conserved protein domain. This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-. Aminotransferases share certain mechanistic features with other pyridoxal- phosphate dependent enzymes, such as the covalent binding of the pyridoxal- phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped into subfamilies. This family is called class-V.

Subfamilies

 * Phosphoserine aminotransferase
 * Cysteine desulfurase
 * Cysteine desulphurase related, unknown function
 * Cysteine desulphurases, SufS
 * Cysteine desulphurase related
 * 2-aminoethylphosphonate—pyruvate transaminase

Human proteins containing this domain
AGXT;     KYNU;      MOCOS;     NFS1;      PSAT1;     SCLY;      TLH6;