TNIK

TRAF2 and NCK-interacting protein kinase is an is_associated_with::enzyme that in humans is encoded by the TNIK is_associated_with::gene.

Function
Germinal center kinases (GCKs), such as TNIK, are characterized by an N-terminal is_associated_with::kinase domain and a C-terminal GCK domain that serves a regulatory function.

Interactions
TNIK has been shown to interact with is_associated_with::KIAA0090, although the significance is unclear. TNIK has been shown to phosphorylate Gelsolin, a protein involved in F-actin depolymerisation thus inducing cytoskeletal changes.