MAGED1

Melanoma-associated antigen D1 is a is_associated_with::protein that in humans is encoded by the MAGED1 is_associated_with::gene.

Function
This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.

Interactions
MAGED1 has been shown to interact with is_associated_with::UNC5A, is_associated_with::PJA1 and is_associated_with::XIAP.