ARHGEF3

Rho guanine nucleotide exchange factor (GEF) 3, also known as ARHGEF3, is a human is_associated_with::gene.

Function
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to the NET1A protein.

Interactions
ARHGEF3 has been shown to interact with is_associated_with::RHOA and is_associated_with::RHOB.