PRINS (gene)

PRINS (psoriasis associated RNA induced by stress) is a is_associated_with::long non-coding RNA. Its expression is induced by stress, and it may have a protective role in cells exposed to stress. It is over-expressed in the skin of patients with is_associated_with::psoriasis. It regulates is_associated_with::G1P3, a is_associated_with::gene encoding a is_associated_with::protein with anti-apoptotic effects in is_associated_with::keratinocytes. Overexpression of PRINS may contribute to psoriasis via the down-regulation of G1P3.