TCF/LEF family

The TCF/LEF family is a group of transcription factors which bind to DNA through a high mobility group domain. They are involved in the Wnt signaling pathway, where they recruit the coactivator beta-catenin to enhancer elements of genes they target. They can also recruit members of the Groucho family of corepressors.

Human members

 * TCF7 (TCF-1)
 * TCF7L1 (TCF-3)
 * TCF7L2 (TCF-4)
 * LEF1