ZEB2

Zinc finger E-box-binding homeobox 2 is a is_associated_with::protein that in humans is encoded by the ZEB2 is_associated_with::gene.

Function
The SMADIP1 gene (also known as SIP1) is a member of the delta-EF1 (TCF8)/Zfh1 family of 2-handed is_associated_with::zinc finger/is_associated_with::homeodomain proteins. SMADIP1 interacts with receptor-mediated, activated full-length SMADs.

Clinical significance
Mutations in the ZEB2 gene are associated with the is_associated_with::Mowat-Wilson syndrome.