Corticotropin-releasing hormone receptor

Corticotropin-releasing hormone receptors (CRHRs), also known known as corticotropin-releasing factor receptors (CRFRs) are a G protein-coupled receptor family that binds corticotropin-releasing hormone (CRH). There are two receptors in the family, designated as type I and 2, each encoded by a separate gene ( and respectively).

Function
CRHRs are important mediators in the stress response. Cells in the anterior lobe of the pituitary gland known as corticotropes express the receptors and will secrete adrenocorticotropic hormone (ACTH) when stimulated.