PAK2

Serine/threonine-protein kinase PAK 2 is an is_associated_with::enzyme that in humans is encoded by the PAK2 is_associated_with::gene.

Function
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

Interactions
PAK2 has been shown to interact with:
 * is_associated_with::Abl gene,
 * is_associated_with::CDC42   and
 * is_associated_with::SH3KBP1.