Rs63749932

rs63749932 is a SNP in the MSH2 gene on chromosome 2, associated with Lynch syndrome (HNPCC).

This variant meets the criteria published in 2013 by the ACMG regarding incidental findings in exome or genome sequencing, as a variant that they do recommend informing a patient about.

Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.

Bethesda guidelines: relation to microsatellite instability and MLH1 promoter methylation in patients with colorectal cancer.

Clinicopathological and molecular genetic analysis of 4 typical Chinese HNPCC families.

Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer.

Switching from tacrolimus to sirolimus halts the appearance of new sebaceous neoplasms in Muir-Torre syndrome.