Liver receptor homolog-1

The liver receptor homolog-1 (LRH-1) also known as NR5A2 (nuclear receptor subfamily 5, group A, member 2) is a is_associated_with::protein that in humans is encoded by the NR5A2 is_associated_with::gene. LRH-1 is a member of the is_associated_with::nuclear receptor family of is_associated_with::intracellular is_associated_with::transcription factors.

LRH-1 plays a critical role in the regulation of development, is_associated_with::cholesterol transport, is_associated_with::bile acid homeostasis and is_associated_with::steroidogenesis.

LRH-1 is important for maintaining pluripotence of stem cells during embryonic development.

Interactions
Liver receptor homolog-1 has been shown to interact with the is_associated_with::small heterodimer partner.