LRRC16A

Leucine rich repeat containing 16A is a is_associated_with::protein that in humans is encoded by the LRRC16A is_associated_with::gene. The gene is also known as LRRC16, CARMIL, CARMIL1 or CARMIL1a.

Model organisms
is_associated_with::Model organisms have been used in the study of LRRC16A function. A conditional is_associated_with::knockout mouse line, called Lrrc16atm1a(KOMP)Wtsi was generated as part of the is_associated_with::International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists — at the is_associated_with::Wellcome Trust Sanger Institute.

Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Twenty two tests were carried out on is_associated_with::mutant mice but no significant abnormalities were observed.