DAZ associated protein 1

DAZ-associated protein 1 is a is_associated_with::protein that in humans is encoded by the DAZAP1 is_associated_with::gene.

Function
In mammals, the is_associated_with::Y chromosome directs the development of the is_associated_with::testes and plays an important role in is_associated_with::spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The is_associated_with::DAZ1 (Deleted in is_associated_with::Azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene is_associated_with::DAZL also involved in germ cell development and gametogenesis. This gene encodes an RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.

Interactions
DAZ associated protein 1 has been shown to interact with is_associated_with::DAZ1.