Rs713041

Two SNPs associated with the antioxidant GPX4 gene, rs713041 and rs757229, are both somewhat correlated (r2=0.61) and are associated with all-cause mortality in breast cancer.

The rs713041(T) allele is associated with an increased risk of death following breast cancer diagnosis, with a hazard ratio of 1.27 per rare allele (CI: 1.13-11.43, p=0.0041).