Rs1051266

rs1051266 (Arg27Cys, 80G>A) is a snp within SLC19A1 (Solute carrier family 19 (folate transporter), member 1).

Cys (A) allele associated with reduced plasma folate

women with GA and AA genotypes had higher red blood cell folate concentrations, not significantly associated with serum folate or homocysteine levels

methotrexate (antifolate drug) uptake lowest in individuals with GG genotype than those with GA or AA genotypes