Keratin 1

Keratin 1 is a member of the is_associated_with::keratin family. It is specifically expressed in the spinous and granular layers of the epidermis with family member is_associated_with::keratin 10. Mutations in this gene have been associated with the variants of is_associated_with::bullous congenital ichthyosiform erythroderma in which the palms and soles of the feet are affected.

Interactions
Keratin 1 has been shown to interact with is_associated_with::Desmoplakin and is_associated_with::PRKCE.