Collagen, type XVI, alpha 1

Collagen alpha-1(XVI) chain is a is_associated_with::protein that in humans is encoded by the COL16A1 is_associated_with::gene.

Function
This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the is_associated_with::extracellular matrix. High levels of type XVI collagen have been found in is_associated_with::fibroblasts and is_associated_with::keratinocytes, and in smooth muscle and is_associated_with::amnion.