FNBP1L

Formin-binding protein 1-like is a is_associated_with::protein that in humans is encoded by the FNBP1L is_associated_with::gene.

Function
The protein encoded by this gene binds to both is_associated_with::CDC42 and is_associated_with::N-WASP. This protein promotes CDC42-induced is_associated_with::actin polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell surface signals to the actin is_associated_with::cytoskeleton. is_associated_with::Alternative splicing results in multiple transcript variants encoding different isoforms.

Clinical significance
FNBP1L polymorphisms, specifically the SNP rs236330 has been associated with normally varying intelligence differences in adults and in children.