Hsp20

Heat shock protein Hsp20 is a family of heat shock proteins.

Prokaryotic and eukaryotic organisms respond to heat shock or other environmental stress by inducing the synthesis of proteins collectively known as heat-shock proteins (hsp). Amongst them is a family of proteins with an average molecular weight of 20 Kd, known as the hsp20 proteins. These seem to act as protein chaperones that can protect other proteins against heat-induced denaturation and aggregation. Hsp20 proteins seem to form large heterooligomeric aggregates. Structurally, this family is characterised by the presence of a conserved C-terminal domain of about 100 residues.

Human proteins containing this domain
CRYAA;    CRYAB;     HSPB1;     HSPB2;     HSPB3;     HSPB6;     HSPB7;     HSPB8; HSPB9;