Eicosanoid receptor

An eicosanoid receptor is an integral membrane protein which detects the presence of eicosanoid signaling molecules. Most, though not all, are G protein-coupled receptors (GPCRs). An example of a non-GPCR receptor that binds eicosanoids is PPAR-γ.

The following is a list of the known human eicosanoid GPCRs grouped according to the type of eicosanoid ligand that each binds:

Leukotriene
Leukotrienes:
 * CysLT1 (Cysteinyl leukotriene receptor 1) -
 * CysLT2 (Cysteinyl leukotriene receptor 2) -
 * BLT1 (Leukotriene B4 receptor) -
 * BLT2 (Leukotriene B4 receptor 2) -

Lipoxin
Lipoxins:
 * LXA4R (Formyl peptide receptor-like 1) -

Oxoeicosanoid
Oxoeicosanoid:
 * Oxoeicosanoid (OXE) receptor 1 -

Prostanoid
Prostanoids:
 * PGD2: DP-(PGD2)
 * DP1 (Prostaglandin D2 receptor) -
 * DP2 (GPR44) -
 * PGE2:
 * EP1-(PGE2) (PTGER1) -
 * EP2-(PGE2) (PTGER2) -
 * EP3-(PGE2) (PTGER3) -
 * EP4-(PGE2) (PTGER4) -
 * PGF2α: FP-(PGF2α) (PTGFR) -
 * PGI2 (prostacyclin): IP-(PGI2) (PTGIR) -
 * TXA2 (thromboxane): TP-(TXA2) (TBXA2R) -