CALU (gene)

Calumenin is a is_associated_with::protein that in humans is encoded by the CALU is_associated_with::gene.

Calumenin (CALU) is a calcium-binding protein localized in the is_associated_with::endoplasmic reticulum (ER) and is involved in such ER functions as is_associated_with::protein folding and sorting. Calumenin is a member of the EF-hand superfamily in the ER and is_associated_with::Golgi apparatus named CERC. CERC is an acronym for its family members Cab-45, reticulocalbin, Erc-55 (is_associated_with::RCN2), and calumenin. The CALU gene encodes a deduced 315-amino acid protein containing 6 EF-hand motifs, 1 potential N-glycosylation site, and a C-terminal ER retention signal. The human and mouse CALU proteins are 98% identical. CALU mRNA is ubiquitously expressed in human tissues and maps to 7q32.