Inositol monophosphatase 3

Inositol monophosphatase 3 also known as inositol monophosphatase domain-containing protein 1 (IMPAD1) is an is_associated_with::enzyme that in humans is encoded by the IMPAD1 is_associated_with::gene.

This gene encodes a member of the is_associated_with::inositol monophosphatase family. The encoded protein is localized to the is_associated_with::Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to is_associated_with::adenosine monophosphate (AMP).

Clinical significance
Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1.