ATXN8OS

Ataxin 8 opposite strand, also known as ATXN8OS, is a human is_associated_with::gene.

Function
SCA8 is an antisense transcript to the is_associated_with::KLHL1 gene (homolog to the Drosophila KELCH gene); it does not itself appear to be protein coding. A CTG trinucleotide repeat expansion that is incorporated into the SCA8 but not the KLHL1 transcript causes spinocerebellar ataxia type 8. Presumably the expansion interferes with normal antisense function of this transcript.