Rs4678

rs4678 is a SNP representing an Arg/Gln variation in the VARS2L gene.

A study of 855 rheumatoid arthritis patients concluded that rs4678 was one of only two SNPs representing an additional susceptibility gene - in addition to HLA-DRB1 - within the MHC region.

There is some inconsistency in this SNP. The reference assembly considers it a A/G while RefSNP calls it a C/T.