DGCR2

The DGCR2 is_associated_with::gene encodes the is_associated_with::protein integral membrane protein DGCR2/IDD in humans.

Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably is_associated_with::DiGeorge syndrome, is_associated_with::velocardiofacial syndrome, is_associated_with::conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in is_associated_with::neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.