SLC6A15

Solute carrier family 6 member 15 (SLC6A15) also known as the sodium-dependent neutral amino acid transporter B(0)AT2 (B0AT2)' is a is_associated_with::protein that in humans is encoded by the SLC6A15 is_associated_with::gene.

Function
SLC6A15 shows structural characteristics of an Na+ and Cl−-dependent is_associated_with::neurotransmitter transporter, including 12 transmembrane (TM) domains, intracellular N and C termini, and large extracellular loops containing multiple N-is_associated_with::glycosylation sites.

Clinical relevance
Variants of this gene linked with depression are associated with reduced SLC6A15 expression in the human hippocampus, as well as decreased volume of this brain region.