MAP1LC3B

Microtubule-associated proteins 1A/1B light chain 3B is a is_associated_with::protein that in humans is encoded by the MAP1LC3B is_associated_with::gene.

Function
The product of this gene is a subunit of neuronal is_associated_with::microtubule-associated is_associated_with::MAP1A and is_associated_with::MAP1B proteins, which are involved in microtubule assembly and important for is_associated_with::neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. The rat homolog is regulated post-translationally by covalent linkage to is_associated_with::phosphatidylethanolamine in the is_associated_with::autophagic membrane, and regulated by is_associated_with::protein kinase A is_associated_with::phosphorylation.