NIN (gene)

Ninein is a is_associated_with::protein that in humans is encoded by the NIN is_associated_with::gene. Ninein, together with its paralog Ninein-like protein is one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the is_associated_with::microtubules minus-ends in is_associated_with::epithelial cells. Localization of this protein to the centrosome requires three is_associated_with::leucine zippers in the central is_associated_with::coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported.