Rs140621530

rs140621530, also known as IVS3+1G>T, is a rare variant in the apolipoprotein C3 APOC3 gene.

As reported in a large study published in 2014, it is one of four loss of function mutations in the APOC3 gene associated with a >40% lower average triglyceride level in individuals carrying one rs140621530(T) allele and a corresponding decrease in coronary artery disease.