Resolvins



Resolvins are compounds that are made by the human body from the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). They are produced by the COX-2 pathway especially in the presence of aspirin. Experimental evidence indicates that resolvins reduce cellular inflammation by inhibiting the production and transportation of inflammatory cells and chemicals to the sites of inflammation.

Other biological actions have been reported, with therapeutical potential such as a reduction in inflammatory pain.

The EPA-derived resolvins are nonclassic eicosanoids.