PITRM1

Pitrilysin metallopeptidase 1 also known as presequence protease, mitochondrial (PreP) and metalloprotease 1 (MTP-1) is an is_associated_with::enzyme that in humans is encoded by the PITRM1 is_associated_with::gene. It is also sometimes called metalloprotease 1 (MP1; ).

Model organisms
is_associated_with::Model organisms have been used in the study of PITRM1 function. A conditional is_associated_with::knockout mouse line called Pitrm1tm1a(KOMP)Wtsi was generated at the is_associated_with::Wellcome Trust Sanger Institute. Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping

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