CAMP responsive element modulator

cAMP-responsive element modulator is a is_associated_with::protein that in humans is encoded by the CREM is_associated_with::gene.

Function
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.

Interactions
CAMP responsive element modulator has been shown to interact with is_associated_with::FHL5.