Nyctalopin

Nyctalopin is a is_associated_with::protein that in humans is encoded by the NYX is_associated_with::gene. It is a is_associated_with::leucine-rich is_associated_with::proteoglycan which is expressed in the eye, spleen and brain in mice. Mutations in this gene cause is_associated_with::congenital stationary night blindness in humans. A is_associated_with::mouse strain called nob (no b-wave) carries a spontaneous mutation leading to a is_associated_with::frameshift in this gene. These mice are used as an is_associated_with::animal model for congenital stationary night blindness.