SLC4A3

Anion exchange protein 3 is a is_associated_with::membrane transport protein that in humans is encoded by the SLC4A3 is_associated_with::gene. AE3 is functionally similar to the is_associated_with::Band 3 Cl−/HCO3− exchange protein but it is expressed primarily in is_associated_with::brain is_associated_with::neurons and in the is_associated_with::heart. Like AE2 its activity is sensitive to is_associated_with::pH. AE3 mutations have been linked to is_associated_with::seizures.