MMP19

Matrix metalloproteinase-19 (MMP-19) also known as matrix metalloproteinase RASI is an is_associated_with::enzyme that in humans is encoded by the MMP19 is_associated_with::gene.

Function
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of is_associated_with::extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This protein is expressed in human epidermis and endothelial cells and it has a role in cellular proliferation, migration, is_associated_with::angiogenesis and adhesion. Multiple transcript variants encoding distinct isoforms have been identified for this gene.