Loricrin

Loricrin is a is_associated_with::protein that in humans is encoded by the LOR is_associated_with::gene.

Function
Loricrin is a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells.

Clinical significance
Mutations in the LOR gene are associated with is_associated_with::Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.