SLC41A3

Solute carrier family 41, member 3 is a is_associated_with::protein that in humans is encoded by the SLC41A3 is_associated_with::gene.

Model organisms
is_associated_with::Model organisms have been used in the study of SLC41A3 function. A conditional is_associated_with::knockout mouse line, called Slc41a3tm1a(KOMP)Wtsi was generated as part of the is_associated_with::International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.

Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Twenty six tests were carried out on is_associated_with::mutant mice and one significant abnormality was observed: is_associated_with::homozygous mutants displayed abnormal locomotor coordination.