Rs3827760

rs3827760, also known as 1540T/C, 370A or Val370Ala, is a SNP in the ectodysplasin A receptor EDAR gene on chromosome 2. The EDAR gene is involved in ectodermal development.

The rs3827760(C) allele is far more prevalent in East Asians than in any other population, and it is used as such in ancestry tests. There are at least three physical characteristics that have been linked to this allele, and pretty much all in a copy-dependent manner as well (inheriting both alleles leads to a stronger expression than inheriting one):


 * Hair follicle thickness
 * Hair straightness (i.e. lack of curliness)
 * Shovel shaped incisors (teeth)

gnxp hair thickness for asians

gnxp blog tooth shape among asians

A picture of shovel shaped incisors is at http://www.flickr.com/photos/39602184@N02/3747590190/