GNL3

Guanine nucleotide-binding protein-like 3 also known as nucleostemin is a is_associated_with::protein that in humans is encoded by the GNL3 is_associated_with::gene. It is found within the is_associated_with::nucleolus that binds is_associated_with::p53. Nucleostemin regulates the is_associated_with::cell cycle and affects is_associated_with::cell differentiation, decreasing in amount as this differentiation progresses. It is a marker for many is_associated_with::stem cells and is_associated_with::cancer cells.

Interactions
GNL3 has been shown to interact with is_associated_with::Mdm2 and is_associated_with::P53.