RELT

Tumor necrosis factor receptor superfamily member 19L is a is_associated_with::protein that in humans is encoded by the RELT is_associated_with::gene.

Function
The protein encoded by this gene is a member of the is_associated_with::TNF-receptor superfamily. This receptor is especially abundant in is_associated_with::hematologic tissues. It has been shown to activate the is_associated_with::NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (is_associated_with::TRAF1). This receptor is capable of stimulating is_associated_with::T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.