SRGN

Serglycin also known as hematopoetic proteoglycan core protein or secretory granule proteoglycan core protein is a is_associated_with::protein that in humans is encoded by the SRGN is_associated_with::gene.

Function
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. is_associated_with::Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a is_associated_with::protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of is_associated_with::granzymes and is_associated_with::perforin, which may serve as a mediator of granule-mediated is_associated_with::apoptosis.