IL36G

Interleukin-36 gamma also known as interleukin-1 family member 9 (IL1F9) is a is_associated_with::protein that in humans is encoded by the IL36G is_associated_with::gene.

Function
The protein encoded by this gene is a member of the is_associated_with::interleukin 1 is_associated_with::cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (is_associated_with::IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (is_associated_with::IL1F5/IL-1 delta). is_associated_with::Interferon-gamma, is_associated_with::tumor necrosis factor-alpha and interleukin 1, beta (is_associated_with::IL1B) are reported to stimulate the expression of this cytokine in is_associated_with::keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or is_associated_with::herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.