LMX1A

LIM homeobox transcription factor 1, alpha, also known as LMX1A, is a is_associated_with::protein which in humans is encoded by the LMX1A is_associated_with::gene.

Function
is_associated_with::Insulin is produced exclusively by the is_associated_with::beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene INS and interact with RNA polymerase to activate or repress transcription. LMX1 is a LIM is_associated_with::homeobox is_associated_with::transcription factor that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin.

Interactions
LMX1A has been shown to interact with is_associated_with::TCF3 and is_associated_with::LHX3.