CLDN5

Claudin-5 is a is_associated_with::protein that in humans is encoded by the CLDN5 is_associated_with::gene. It belongs to the group of is_associated_with::claudins.

Function
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.

Interactions
CLDN5 has been shown to interact with is_associated_with::CLDN1 and is_associated_with::CLDN3.