NPR1

Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A), also known as NPR1, is an is_associated_with::atrial natriuretic peptide receptor. In humans it is encoded by the NPR1 is_associated_with::gene.

Function
NPR1 is a membrane-bound is_associated_with::guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP and BNP, respectively).

It is localized in the kidney where it results in is_associated_with::natriuresis upon binding to natriuretic peptides. However, it is found in even greater quantity in the lungs and is_associated_with::adipocytes.