OCRL

Inositol polyphosphate 5-phosphatase OCRL-1 (INPP5F), also known as Lowe oculocerebrorenal syndrome protein, is an is_associated_with::enzyme encoded by the OCRL is_associated_with::gene located on the is_associated_with::X chromosome in humans.

This gene encodes a is_associated_with::phosphatase enzyme involved in is_associated_with::actin polymerization, and is found in the trans-Golgi network.

Mutation in this gene are associated with is_associated_with::oculocerebrorenal syndrome and also with is_associated_with::Dent's disease.