Rs28928905

rs28928905, also known as Ala490Thr or A490T, is a SNP in the KCNH2 gene on chromosome 7.

The rs28928905(A) allele has been reported to be associated with bradycardia-induced long QT syndrome; see OMIM for discussion.

This variant meets the criteria published in 2013 by the ACMG regarding incidental findings in exome or genome sequencing, as a variant that they do recommend informing a patient about.