HSPB6

Heat shock protein beta-6 is a is_associated_with::protein that in humans is encoded by the HSPB6 is_associated_with::gene.

HSPB6 also known as is_associated_with::hsp20 is a 17-kDa member of the small heat shock family of proteins. HSPB6 was first identified in 1994 when it was isolated from rat and human skeletal muscle as a complex with is_associated_with::HSPB1 (also known as is_associated_with::HSP27) and is_associated_with::HSPB5 (also known as αB-crystallin).

HSPB6 is expressed in multiple tissues; however, HSPB6 is most highly and constitutively expressed in different types of muscle including vascular, airway, colonic, bladder, uterine smooth muscle, cardiac muscle and skeletal muscle. HSPB6 has specific functions for vasodilation, platelet function, and is_associated_with::insulin resistance and in smooth and cardiac muscle.