RNF4

RING finger protein 4 is a is_associated_with::protein that in humans is encoded by the RNF4 is_associated_with::gene.

The protein encoded by this gene contains a is_associated_with::RING finger domain and acts as a is_associated_with::transcription factor. This protein has been shown to interact with, and inhibit the activity of, is_associated_with::TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/is_associated_with::PATZ1 is found to interact with this protein, and thus reduce the enhancement of is_associated_with::androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in is_associated_with::spermatogenesis.

Interactions
RNF4 has been shown to interact with is_associated_with::TCF20, is_associated_with::PATZ1 and is_associated_with::Androgen receptor.