Rs1062613

Rs1062613 (C178T, Pro16Ser) is located within the 5' UTR of HTR3A and may effect HTR3A expression.

reporter constructs containing the T allele showed increased HTR3A expression compared to the C allele

CC and CT carriers associated with higher harm avoidance (p = 0.04) scores in 2 sample groups of Swedish women (366 in total), and non-conformity in 1 sample

no significant association between treatment-resistant schizophrenia and Rs1062613, however, maintenance neuroleptic dose was significantly higher for TT carriers (p = 0.041)


 * is_associated_with_disease::Irritable bowel syndrome
 * is_associated_with_disease::Schizophrenia