APPL2

DCC-interacting protein 13-beta is a is_associated_with::protein that in humans is encoded by the APPL2 is_associated_with::gene.

Model organisms
is_associated_with::Model organisms have been used in the study of APPL2 function. A conditional is_associated_with::knockout mouse line, called Appl2tm1a(KOMP)Wtsi was generated as part of the is_associated_with::International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists — at the is_associated_with::Wellcome Trust Sanger Institute.

Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Twenty three tests were carried out on is_associated_with::mutant mice, but no significant abnormalities were observed.