Keratin 14

Keratin 14 is a member of the is_associated_with::type I keratin family of intermediate filament proteins. Keratin 14 was the first type I keratin sequence determined. Keratin 14 is also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14). In humans it is encoded by the KRT14 is_associated_with::gene.

Keratin 14 is usually found as a heterodimer with type II is_associated_with::keratin 5 and form the is_associated_with::cytoskeleton of is_associated_with::epithelial cells.

Pathology
Mutations in the genes for these keratins are associated with is_associated_with::epidermolysis bullosa simplex and is_associated_with::Dermatopathia pigmentosa reticularis, both of which are autosomal dominant mutations.