ADAM33

Disintegrin and metalloproteinase domain-containing protein 33 is an is_associated_with::enzyme that in humans is encoded by the ADAM33 is_associated_with::gene.

Function
This gene encodes a member of the ADAM (is_associated_with::a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom is_associated_with::disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including is_associated_with::fertilization, muscle development, and is_associated_with::neurogenesis. This protein is a type I is_associated_with::transmembrane protein implicated in is_associated_with::asthma and is_associated_with::bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.