ATP6AP2

The renin receptor also known as ATPase H(+)-transporting lysosomal accessory protein 2, or the prorenin receptor, is a is_associated_with::protein that in humans is encoded by the ATP6AP2 is_associated_with::gene.

Function
The renin receptor binds is_associated_with::renin and prorenin. Binding of renin to this receptor induces the conversion of angiotensinogen to angiotensin I.

This protein is associated with adenosine triphosphatases (is_associated_with::ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. This protein has been found associated with the transmembrane sector of the V-type ATPases.