Rs600491

men carrying the T allele of rs600491 had an increased risk of Alzheimer's disease (OR 1.7 95% CI 1.2-2.4; P = 0.004, Bonferroni corrected P = 0.048 with 12 tests).

rs638944(T) and rs600491(C) protective haplotype TC with frequency of 0.22 in cases and 0.30 in controls (P < 0.001)

rs638944(G) and rs600491(C) risk haplotype GC with frequency of 0.10 in cases and 0.05 in controls (P < 0.001)

Alzheimer's disease cases that carry rs718265(G;G) had lower levels of Abeta(42)