Rs3087456

This SNP has been linked to increased risk of adrenal insufficiency However. there is mixed information regarding several other autoimmune diseases in a german population

Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups.

An evaluation of 4,000 UK RA patients did not show any risk associated with this SNP.

A study of a Swedish cohort of 446 myasthenia gravis (MG) patients and 1866 controls found no significant association of the SNP with MG, either in the patient group as a whole or in any clinical subgroup.


 * is_associated_with_disease::Multiple sclerosis
 * is_associated_with_disease::Rheumatoid arthritis
 * is_associated_with_disease::Diabetes mellitus
 * is_associated_with_disease::Systemic lupus erythematosus
 * is_associated_with_disease::Myasthenia gravis
 * is_associated_with_disease::Celiac disease
 * is_associated_with_disease::Crohn's disease
 * is_associated_with_disease::Syndrome