TACSTD2

Tumor-associated calcium signal transducer 2 is a is_associated_with::protein that in humans is encoded by the TACSTD2 is_associated_with::gene.

This is_associated_with::intronless gene encodes a carcinoma-associated is_associated_with::antigen defined by the monoclonal antibody is_associated_with::GA733. This antigen is a member of a family including at least two type I is_associated_with::membrane proteins. It transduces an intracellular is_associated_with::calcium signal and acts as a is_associated_with::cell surface receptor. Mutations of this gene result in is_associated_with::gelatinous drop-like corneal dystrophy, an is_associated_with::autosomal recessive disorder characterized by severe corneal is_associated_with::amyloidosis leading to is_associated_with::blindness.