Natriuretic peptide precursor C

Natriuretic peptide precursor C, also known as NPPC, is a is_associated_with::protein that in humans is encoded by the NPPC is_associated_with::gene. The precursor NPPC protein is cleaved to the 22 is_associated_with::amino acid is_associated_with::peptide C-type natriuretic peptide (CNP).

Function
is_associated_with::Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent is_associated_with::natriuretic, is_associated_with::diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control. Unlike ANP and BNP, CNP does not have direct natriuretic activity. This is because CNP is a selective is_associated_with::agonist for the B-type natriuretic receptor (NPRB) whereas ANP and BNP are selective for NPRA.