ARID1B

AT-rich interactive domain-containing protein 1B is a is_associated_with::protein that in humans is encoded by the ARID1B is_associated_with::gene. ARID1B is a component of the human is_associated_with::SWI/SNF chromatin remodeling complex.

Clinical significance
Germline mutations in ARID1B are associated with is_associated_with::Coffin-Siris syndrome. Somatic mutations in ARID1B are associated with several cancer subtypes, suggesting that it is a tumor suppressor gene.

Interactions
ARID1B has been shown to interact with is_associated_with::SMARCA4 and is_associated_with::SMARCA2.