GDF7

Growth differentiation factor 7 (GDF7) is a is_associated_with::protein that in humans is encoded by the GDF7 is_associated_with::gene.

GDF7 belongs to the is_associated_with::transforming growth factor beta superfamily that is specifically found in a signaling center known as the is_associated_with::roof plate that is located in the developing nervous system of is_associated_with::embryos. The roof plate is required for the generation of several classes of is_associated_with::spinal cord dorsal is_associated_with::interneurons; GDF7 specifically induces the formation of is_associated_with::sensory neurons in the is_associated_with::dorsal spinal cord from is_associated_with::neural crest cells by generating signals within the roof plate.