Eukaryotic translation initiation factor 4 gamma

Eukaryotic translation initiation factor 4 gamma 1 is a is_associated_with::protein that in humans is encoded by the EIF4G1 is_associated_with::gene.

Function
The protein encoded by this gene is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure, and recruitment of mRNA to the ribosome. Alternative splicing results in five transcript variants encoding four distinct isoforms.

Interactions
Eukaryotic translation initiation factor 4 gamma has been shown to interact with is_associated_with::MKNK1, is_associated_with::EIF4A1,  is_associated_with::EIF4E,    is_associated_with::MKNK2 and is_associated_with::PABPC1.