Leukocyte receptor tyrosine kinase

Leukocyte receptor tyrosine kinase is an is_associated_with::enzyme that in humans is encoded by the LTK is_associated_with::gene.

Function
The protein encoded by this gene is a member of the ALK/LTK receptor family of receptor tyrosine kinases (RTKs) whose ligand is unknown. Closely related to the insulin receptor family of RTKs. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Interactions
LTK has been shown to interact with is_associated_with::IRS-1, Shc, and is_associated_with::PIK3R1.