CASC3

Protein CASC3 is a is_associated_with::protein that in humans is encoded by the CASC3 is_associated_with::gene.

Function
The product of this gene is a core component of the is_associated_with::exon junction complex (EJC), a protein complex that is deposited on spliced is_associated_with::mRNAs at exon-exon junctions and functions in is_associated_with::nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the is_associated_with::cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.