SEMA4A

Semaphorin-4A is a is_associated_with::protein that in humans is encoded by the SEMA4A is_associated_with::gene.

Function
SEMA4A is a member of the is_associated_with::semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in guidance of axonal migration during neuronal development and in immune responses.[supplied by OMIM]

Clinical significance
A germline variant in SEMA4A (V78M) has been demonstrated to confer risk for is_associated_with::colorectal cancer type X.