Rs1165205

rs1165205 is a SNP in the SLC17A3 gene on ch 6.

A large study totaling 7,699 participants in the Framingham cohort and 4,148 participants in the Rotterdam cohort was conducted, with genome-wide significant SNPs then replicated in 11,000+ Caucasian and ~4,000 African-American individuals who took part in the study of Atherosclerosis Risk in Communities (ARIC). This study calculated an odds ratio of 0.85 for rs1165205, (CI: 0.77-0.94, p = 0.002). A genetic score comprised of this SNP plus 2 others may stratify risk for gout.

See also: 23andMe blog gout
 * rs2231142(T) 1.7x
 * rs16890979(C) 1.7x
 * rs1165205(A) 1.2x