Rs3740199

Authors of this study of just 189 subjects conclude that rs3740199 polymorphism may affect occurrence of knee osteoarthritis and its progression (p = 0.018), and even speculate that this SNP's effect is "remarkably gender-dependent and anatomical site-specific". Of course, another alternative is that it's just another case of overinterpretation based on having too few samples for a properly powered SNP study. Only time will tell.

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.