WIF1

Wnt inhibitory factor 1 is a is_associated_with::protein that in humans is encoded by the WIF1 is_associated_with::gene. WIF1 is a is_associated_with::lipid-binding protein that binds to Wnt proteins and prevents them from triggering signalling.

Function
WNT proteins are extracellular signaling molecules involved in the control of is_associated_with::embryonic development. This gene encodes a secreted protein, which binds WNT proteins and inhibits their activities. This protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. It may be involved in is_associated_with::mesoderm segmentation. This protein is found to be present in fish, amphibia and mammals.