REG1A

Lithostathine-1-alpha also known as islet cells regeneration factor (ICRF) or islet of Langerhans regenerating protein (REG) is a is_associated_with::protein that in humans is encoded by the REG1A is_associated_with::gene.

Function
This protein is a type I subclass member of the is_associated_with::Regenerating protein family. The Reg protein family is a multi protein family grouped into four subclasses, types I, II, III and IV based on the primary structures of the proteins. This protein that is secreted by the is_associated_with::exocrine pancreas. It is associated with is_associated_with::islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members is_associated_with::REG1B, REGL, PAP and this gene are tandomly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.