KCNJ10

ATP-sensitive inward rectifier potassium channel 10 is a is_associated_with::protein that in humans is encoded by the KCNJ10 is_associated_with::gene.

EAST syndrome
Humans with is_associated_with::mutations in the KCNJ10 gene that cause loss of function in related K+ channels can display is_associated_with::Epilepsy, is_associated_with::Ataxia, is_associated_with::Sensorineural deafness and is_associated_with::Tubulopathy, the is_associated_with::EAST syndrome (is_associated_with::Gitelman syndrome phenotype) reflecting roles for KCNJ10 gene products in the brain, is_associated_with::inner ear and is_associated_with::kidney. The Kir4.1 channel is expressed in the is_associated_with::Stria vascularis and is essential for formation of the is_associated_with::endolymph, the fluid that surrounds the mechanosensitive is_associated_with::stereocilia of the sensory is_associated_with::hair cells that make hearing possible.

Interactions
KCNJ10 has been shown to interact with is_associated_with::Interleukin 16.