Diiodotyrosine

Diiodotyrosine (DIT) is a precursor of thyroid hormone and results from iodization of monoiodotyrosine at the other meta- position on the phenol ring.

DIT is a modulator of thyroid peroxidase. When combined with monoiodotyrosine in the colloid of the thyroid follicle, triiodothyronine is formed. Two molecules of DIT combine to make thyroxine.