Rs1343151

rs1343151 is one of several SNPs in the IL23R gene that has been shown in a large (over 1,000 Caucasian patients) study to be associated with ankylosing spondylitis. The odds ratio is 0.8 (p=1.0x10e-5).[PMID 17952073, PMID 18037607]

rs1343151 with rheumatoid arthritis (OR=1.14 [1.06-1.22], P=4x10-4)

rs1343151 was not associated with rheumatoid arthritis in a study of 1,200+ Korean patients.

A;A homozygous individuals showed a strongly reduced risk of Crohn's Disease compared those who were G;G homozygous.


 * is_associated_with_disease::Temporal arteritis
 * is_associated_with_disease::Ankylosing spondylitis
 * is_associated_with_disease::Rheumatoid arthritis