BACH2

Transcription regulator protein BACH2 is a is_associated_with::protein that in humans is encoded by the BACH2 is_associated_with::gene. It contains a is_associated_with::BTB/POZ domain at its N-terminus which forms a disulphide-linked dimer and a bZip_Maf domain at the C-terminus.

Model organisms
is_associated_with::Model organisms have been used in the study of BACH2 function. A conditional is_associated_with::knockout mouse line called Bach2tm1a(EUCOMM)Wtsi was generated at the is_associated_with::Wellcome Trust Sanger Institute. Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping - in-depth bone and cartilage phenotyping