BCAM

Basal cell adhesion molecule is a is_associated_with::protein that in humans is encoded by the BCAM is_associated_with::gene. BCAM has also recently been designated CD239 (is_associated_with::cluster of differentiation 239).

Function
Lutheran blood group glycoprotein is a member of the is_associated_with::immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, is_associated_with::N-terminus, extracellular is_associated_with::immunoglobulin domains, a single transmembrane domain, and a short, is_associated_with::C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two transcript variants encoding different isoforms have been found for this gene.

Interactions
BCAM has been shown to interact with is_associated_with::Laminin, alpha 5.