Rs12316150

rs12316150, a SNP also known as +1071, is located in the 3' untranslated region of the oxidized low density lipoprotein (lectin-like) receptor 1 OLR1 gene, which is also known as the LOX-1 gene.

The rs12316150 risk allele has been associated with increased risk for Alzheimer's disease in several studies of ~200 Southern Italian Alzheimer patients, but only within the context of a haplotype including one or both of neighboring SNPs rs1050283 and rs669.[PMID 15860461, PMID 18191876]