PRAME

Melanoma antigen preferentially expressed in tumors is a is_associated_with::protein that in humans is encoded by the PRAME is_associated_with::gene.

Model organisms
is_associated_with::Model organisms have been used in the study of PRAME function. A conditional is_associated_with::knockout mouse line called Prametm1a(KOMP)Wtsi was generated at the is_associated_with::Wellcome Trust Sanger Institute. Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping

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