FARP2

FERM, RhoGEF and pleckstrin domain-containing protein 2 is a is_associated_with::protein that in humans is encoded by the FARP2 is_associated_with::gene.

Model organisms
is_associated_with::Model organisms have been used in the study of FARP2 function. A conditional is_associated_with::knockout mouse line, called Farp2tm1a(KOMP)Wtsi was generated as part of the is_associated_with::International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.

Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Twenty four tests were carried out on is_associated_with::mutant mice and two significant abnormalities were observed. is_associated_with::Homozygous mutant animals had a thickened is_associated_with::cerebral cortex and displayed abnormal hair shedding.

Interactions
FARP2 has been shown to interact with is_associated_with::PDZK1.