Rs12770228

rs12770228 is a SNP in a region on ch 10p12.31 designated as the chromosome 10 open reading frame 114 C10orf114; it is just upstream of the MLLT10 gene.

A study of ~1,600 patients with meningioma, all of European ancestry, concluded that increased risk for the disease was associated with rs12770228(A) alleles. The odds ratio was 1.37 (CI: 1.18-1.59, p = 4 x 10e-4). A nearby SNP, rs11012732, was also linked to meningioma risk.