SEPT6

Septin-6 is a is_associated_with::protein that in humans is encoded by the SEPT6 is_associated_with::gene.

Function
This gene is a member of the is_associated_with::septin family of is_associated_with::GTPases. Members of this family are required for is_associated_with::cytokinesis. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Clinical significance
One version of pediatric is_associated_with::acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins.

Interactions
SEPT6 has been shown to interact with is_associated_with::SEPT2.