Rs121918070

rs121918070, also known as Thr60Ala, Thr80Ala, T60A, T80A, and 238A>G, is a mutation in the transthyretin TTR gene.

The risk allele for this SNP, rs121918070(G), is considered causative for TTR-related familial amyloid polyneuropathy, often manifesting as heart-related symptoms, in those carrying either one or two copies.