GPR120

G-protein coupled receptor 120 is a is_associated_with::protein that in humans is encoded by the GPR120 is_associated_with::gene.

GPR120 is a member of the rhodopsin family of is_associated_with::G protein-coupled receptors (GPRs).

GPR120 has also been shown to mediate the anti-inflammatory and is_associated_with::insulin-sensitizing effects of is_associated_with::omega 3 fatty acids. Lack of GPR120 is responsible for reduced fat metabolism, thereby leading to is_associated_with::obesity.

Additionally, GPR120 has been implicated to be involved in the ability to is_associated_with::taste fats. It is expressed in is_associated_with::taste bud cells (specifically cell type II, which contain other G-protein coupled taste receptors), and its absence leads to reduced preference to two types of fatty acid (is_associated_with::linoleic acid and is_associated_with::oleic acid), as well as decreased neuronal response to oral fatty acids.