Rs28897759

BRCA2 Asn3124Ile or N3124I mutation. The significance is unclear; it is not listed as a causal mutation for breast cancer in UMD, and there is conflicting evidence in ClinVar, with some labs indicating it is pathogenic but others reporting it is of unknown significance.

This variant meets the criteria published in 2013 by the ACMG regarding incidental findings in exome or genome sequencing, as a variant that they do recommend informing a patient about.