CCL17

Chemokine (C-C motif) ligand 17 (CCL17) is a small is_associated_with::cytokine belonging to the CC is_associated_with::chemokine family is also known as thymus and activation regulated chemokine (TARC). CCL17 is expressed constitutively in thymus, but only transiently in is_associated_with::phytohemagglutinin-stimulated peripheral blood mononuclear cells. This chemokine specifically binds and induces is_associated_with::chemotaxis in is_associated_with::T cells and elicits its effects by interacting with the chemokine receptor CCR4. The gene for CCL17 is located on is_associated_with::chromosome 16, in humans, along with other chemokines called is_associated_with::CCL22 and is_associated_with::CX3CL1.