EIF2S2

Eukaryotic translation initiation factor 2 subunit 2 is a is_associated_with::protein that in humans is encoded by the EIF2S2 is_associated_with::gene.

Function
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of is_associated_with::protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a is_associated_with::40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta (this article), and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation.

Regulation
Both eIF2-alpha and eIF2-beta expression is regulated by the is_associated_with::NRF1 is_associated_with::transcription factor.