PEX10

Peroxisome biogenesis factor 10 is a is_associated_with::protein that in humans is encoded by the PEX10 is_associated_with::gene. Alternative splicing results in two transcript variants encoding different isoforms.

Function
Peroxisome biogenesis factor 10 is involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane.

Clinical significance
Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal is_associated_with::biogenesis disorders, ranging from neonatal is_associated_with::adrenoleukodystrophy to is_associated_with::Zellweger syndrome.

Interactions
PEX10 has been shown to interact with is_associated_with::PEX12 and is_associated_with::PEX19.