AKAP8

A-kinase anchor protein 8 is an is_associated_with::enzyme that, in humans, is encoded by the AKAP8 is_associated_with::gene.

Function
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of is_associated_with::protein kinase A (PKA) and confining it to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is located in the nucleus during is_associated_with::interphase and is redistributed to distinct locations during is_associated_with::mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.

Interactions
AKAP8 has been demonstrated to interact with:
 * is_associated_with::Cyclin D3
 * is_associated_with::DDX5,
 * is_associated_with::MCM2,
 * is_associated_with::MYCBP, and
 * is_associated_with::PRKAR2A.