Rs2811712

rs2811712 is a SNP associated with physical function in older individuals, and thus indirectly associated with longevity.

In a study ultimately totaling over 3,300 elderly Caucasian individuals, the less common rs2811712(G) allele was associated with reduced physical impairment. Overall, severely limited physical function was present in 15.0% of the more common rs2811712(A;A) homozygotes, versus 7.0% of the rs2811712(G;G) homozygotes, yielding a per risk allele odds ratio of 1.48 (CI: 1.17-1.88, p=0.001).

Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.

Consortium analysis of 7 candidate SNPs for ovarian cancer.

Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.

INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis.

Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.


 * is_associated_with_disease::Atherosclerosis
 * is_associated_with_disease::Ovarian cancer
 * is_associated_with_disease::Breast cancer