Gastrin-releasing peptide receptor

The gastrin-releasing peptide receptor (GRPR), now properly known as BB2 is a is_associated_with::G protein-coupled receptor whose is_associated_with::endogenous ligand is is_associated_with::gastrin releasing peptide. In humans it is highly expressed in the is_associated_with::pancreas and is also expressed in the is_associated_with::stomach, is_associated_with::adrenal cortex and is_associated_with::brain.

The is_associated_with::transcription factor is_associated_with::CREB is a regulator of human GRP-R expression in colon cancer.