Monooxygenase DBH-like 1

DBH-like monooxygenase protein 1, also known as monooxygenase X, is an is_associated_with::enzyme that in humans is encoded by the MOXD1 is_associated_with::gene.

DBH-like 1 maintains many of the structural features of dopamine beta-is_associated_with::monooxygenase DBH. Since Peptidylglycine alpha-hydroxylating monooxygenase (PHM; EC 1.14.17.3) is homologous to dopamine beta-monooxygenase (DBM; EC 1.14.17.1) this concerns a structural basis for a new family of copper type II, significantly specific for ascorbate-dependent monooxygenases based on the corresponding mouse homolog. The pathway of is_associated_with::catecholamine synthesis is a possible catecholamine-binding metabolic copper enzyme domain, a neuron-like property encoding MOX without a signal sequence enzyme metabolism resolving the is_associated_with::monooxygenase X chemical pathway of   an unknown substrate, is_associated_with::exogenous MOX is not secreted, and it localizes throughout the is_associated_with::endoplasmic reticulum, in both is_associated_with::endocrine or nonendocrine cells.

Deficiency
DBH deficiency has been treated effectively with L-threo-3,4-dihydroxyphenylserine (DOPS).