HSD3B2

HSD3B2 is a human is_associated_with::gene that encodes for 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type II or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2. It is expressed principally in steroidogenic tissues and is essential for is_associated_with::steroid hormone production. A notable exception is the is_associated_with::placenta, where is_associated_with::HSD3B1 is critical for is_associated_with::progesterone production by this tissue.

Mutations in the HSD3B2 gene result in the condition is_associated_with::congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency.