Rs13333226

rs13333226 is a SNP in the 5' region of uromodulin UMOD gene.

A large GWAS study ultimately totaling over 20,000 cases and almost as many controls concluded that, compared to the far more common allele, the rarer rs13333226(G) allele is associated with a (slightly) lower risk of hypertension (odds ratio 0.87, CI: 0.84-0.91) as well as a 7.7% reduction per allele for risk of cardiovascular events after adjusting for age, sex, BMI, and smoking status (hazard ratio?0.923, CI: 0.860-0.991; p?=?0.027).

High Blood Pressure (Hypertension)

Kidney Disease


 * is_associated_with_disease::Kidney disease
 * is_associated_with_disease::Hypertension