Arylsulfatase A

Arylsulfatase A (or cerebroside-sulfatase) is an is_associated_with::enzyme that breaks down sulfatides, namely cerebroside 3-sulfate into is_associated_with::cerebroside and is_associated_with::sulfate. In humans, arylsulfatase A is encoded by the ARSA is_associated_with::gene.

Pathology
A deficiency is associated with is_associated_with::metachromatic leukodystrophy, an is_associated_with::autosomal is_associated_with::recessive disease.

Enzyme Regulation
Arylsulfatase A is inhibited by phosphate, which forms a covalent bond with the active site 3-oxoalanine.