PRRX2

Paired mesoderm homeobox protein 2 is a is_associated_with::protein that in humans is encoded by the PRRX2 is_associated_with::gene.

Function
The DNA-associated protein encoded by this gene is a member of the paired family of is_associated_with::homeobox proteins. Expression is localized to proliferating fetal is_associated_with::fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.