PFKP

Phosphofructokinase, platelet, also known as PFKP is an is_associated_with::enzyme which in humans is encoded by the PFKP is_associated_with::gene.

Function
The PFKP gene encodes the platelet isoform of is_associated_with::phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of is_associated_with::fructose 6-phosphate to is_associated_with::fructose 1,6-bisphosphate and is a key regulatory enzyme in is_associated_with::glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (is_associated_with::PFKM) and liver (is_associated_with::PFKL) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Full tetrameric phosphofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.