KLK6

Kallikrein-6 is a is_associated_with::protein that in humans is encoded by the KLK6 is_associated_with::gene.

Function
is_associated_with::Kallikreins are a subgroup of serine is_associated_with::proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in is_associated_with::carcinogenesis and some have potential as novel cancer and other disease is_associated_with::biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the is_associated_with::amyloid precursor protein, suggesting a potential for involvement in is_associated_with::Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.