NEK8

Serine/threonine-protein kinase Nek8, also known as never in mitosis A-related kinase 8, is an is_associated_with::enzyme that in humans is encoded by the NEK8 is_associated_with::gene.

Function
Nek8 is a member of the is_associated_with::serine/threonine-specific protein kinase family related to NIMA (never in mitosis, gene A) of is_associated_with::Aspergillus nidulans. The encoded protein may play a role in is_associated_with::cell cycle progression from G2 to M phase.

Clinical significance
Mutations in the NEK8 gene associated with is_associated_with::nephronophthisis.