Alpha-1D adrenergic receptor

The alpha-1D adrenergic receptor (α1D adrenoreceptor), also known as ADRA1D, is an is_associated_with::alpha-1 adrenergic receptor, and also denotes the human is_associated_with::gene encoding it.

Receptor
There are 3 alpha-1 adrenergic receptor subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. They activate mitogenic responses and regulate growth and proliferation of many cells.

Gene
This gene encodes alpha-1D-adrenergic receptor. Similar to is_associated_with::alpha-1B-adrenergic receptor gene, this gene comprises 2 is_associated_with::exons and a single is_associated_with::intron that interrupts the coding region.

Ligands

 * Antagonists
 * A-315456
 * BMY 7378 (also α2C antagonist)