FIGLA

Folliculogenesis-specific basic helix-loop-helix, also known as factor in the germline alpha (FIGalpha) or transcription factor FIGa, is a is_associated_with::protein that in humans is encoded by the FIGLA is_associated_with::gene.

Function
This gene encodes a protein that functions in postnatal is_associated_with::oocyte-specific gene expression. The protein is a is_associated_with::basic helix-loop-helix transcription factor that regulates multiple is_associated_with::oocyte-specific genes, including genes involved in is_associated_with::folliculogenesis and those that encode the is_associated_with::zona pellucida.

Clinical significance
Mutation in the FIGLA gene are associated with is_associated_with::premature ovarian failure.