Rs6602024


 * Within the PFKP gene, rs6602024 showed very strong association with BMI (p = 4.9 * 10-6). Homozygotes for the rare "A" allele of this SNP (minor allele frequency = 0.12) were 1.8 BMI units heavier than homozygotes for the common "G" allele.
 * They did not replicate association between rs6602024 and obesity-related traits in the GenNet sample, although they found that in European Americans, Hispanic Americans and African Americans, homozygotes for the rare "A" allele where, on average, 1.0 - 3.0 BMI units heavier than homozygotes for the more common "G" allele.

Furthermore, a study of 18,000 Danish subjects also failed to find any direct role for this SNP in the development of obesity.


 * is_associated_with_disease::Obesity