SF3B4

Splicing factor 3B subunit 4 is a is_associated_with::protein that in humans is encoded by the SF3B4 is_associated_with::gene.

Disease Associations
In 2012, Canadian researchers belonging to the FORGE (Finding of Rare disease GEnes) consortium identified new dominant mutations in SF3B4 as the cause of is_associated_with::Nager syndrome, a rare type of mandibulofacial dysostosis with associated limb malformations.

Interactions
SF3B4 has been shown to interact with is_associated_with::CDC5L, is_associated_with::BMPR1A and is_associated_with::SF3B2.