POLE (gene)

DNA polymerase epsilon catalytic subunit is an is_associated_with::enzyme that in humans is encoded by the POLE is_associated_with::gene. It is the central catalytic subunit of is_associated_with::DNA polymerase epsilon.

Clinical significance
POLE, along with is_associated_with::POLD1, has recently been associated with multiple adenoma.

Interactions
POLE has been shown to interact with is_associated_with::RAD17.