BCL11B

B-cell lymphoma/leukemia 11B is a is_associated_with::protein that in humans is encoded by the BCL11B is_associated_with::gene.

Function
This gene encodes a C2H2-type is_associated_with::zinc finger protein and is closely related to is_associated_with::BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined, but it could also be involved in some malignancies. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.

Recent research suggests that BCL11B is crucial for is_associated_with::ameloblasts (the cells that produce is_associated_with::tooth enamel) to form and work properly.

Interactions
BCL11B has been shown to interact with is_associated_with::COUP-TFI.