FAM73B

family with sequence similarity 73, member B, also known as FAM73B, is a human is_associated_with::gene.

Model organisms
is_associated_with::Model organisms have been used in the study of FAM73B function. A conditional is_associated_with::knockout mouse line, called Fam73btm1a(KOMP)Wtsi was generated as part of the is_associated_with::International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.

Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Twenty four tests were carried out on is_associated_with::mutant mice and six significant abnormalities were observed. is_associated_with::Homozygous mutant animals had a decreased body weight, altered body composition, abnormal tooth morphology, is_associated_with::hypoalbuminemia, decreased is_associated_with::bone mineral content and strength, and an increased susceptibility to is_associated_with::bacterial infection.