Rs33950507

rs33950507 is a SNP found in the beta hemoglobin HBB gene, not far from the well-known SNP associated with malarial resistance (rs334, Hb S). This SNP gives rise to the "Hb E", or hemoglobin E, form of hemoglobin as the HBB forms are commonly named. It is found primarily in Southeast Asia.

rs33950507(A) is associated with somewhat increased malarial resistance, and in homozygous (A;A) state, with mild hypochromic microcytic anemia.

Microarray-based estimation of SNP allele-frequency in pooled DNA using the Langmuir kinetic model.