OGN (gene)

Osteoglycin (also called mimecan), encoded by the OGN gene, is a human is_associated_with::protein.

This gene encodes a protein which induces ectopic bone formation in conjunction with is_associated_with::transforming growth factor beta. This protein is a small proteoglycan which contains tandem is_associated_with::leucine-rich repeats (LRR). The gene expresses three transcript variants.

The level of expression of this gene has been correlated with is_associated_with::enlarged hearts and more specifically is_associated_with::left ventricular hypertrophy.