FOXJ1

Forkhead box protein J1 is a is_associated_with::protein that in humans is encoded by the FOXJ1 is_associated_with::gene. It has been shown that this gene is a is_associated_with::transcription factor involved in ciliogenesis.

Function
This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry.

Clinical significance
Polymorphisms in this gene are associated with is_associated_with::systemic lupus erythematosus and is_associated_with::allergic rhinitis.