Rs3792876

NOTE: information for rs1050152 was accidentally entered for this SNP, rs3792876. Although the SNPs are in the same gene, the original reference does not specifically refer to rs3792876 and the degree of linkage has not been confirmed.

rs1051052, a SNP in the SLC22A4 gene known as L503F, has been associated with an autoimmune disease, in this case, Crohn's disease, odds ratio = 2.1 (CI = 1.31&#226;&#8364;&#8220;3.39, p = 0.002), based on a study of 203 cases and 200 controls. The risk allele is rs1050152(T).

A nearby SNP in the promoter region of the SLC22A5 gene defines a haplotype along with rs3792876, with odds ratio reported as similar for either SNP or the haplotype.

rs2073838 and rs3792876 replicated for rheumatoid arthritis in Japanese, but not Caucasian populations.

rs3792876 failed to showed a statistically significant association with rheumatoid arthritis