TEC (gene)

Tyrosine-protein kinase Tec is an is_associated_with::enzyme that in humans is encoded by the TEC is_associated_with::gene.

Function
The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein-coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Interactions
TEC (gene) has been shown to interact with:


 * is_associated_with::ARHGEF12,
 * is_associated_with::CD117,
 * is_associated_with::DOK1,
 * is_associated_with::GNA12,
 * is_associated_with::Janus kinase 2,  and
 * is_associated_with::Suppressor of cytokine signaling 1.