Red hair



Red hair occurs on approximately 1–2% of the human population. It occurs more frequently (2–6%) in people of northern or western European ancestry, and less frequently in other populations. Red hair appears in people with two copies of a recessive gene on chromosome 16 which causes a mutation in the MC1R protein.

Red hair varies from a deep burgundy through burnt orange to bright copper. It is characterized by high levels of the reddish pigment pheomelanin and relatively low levels of the dark pigment eumelanin. The term redhead (originally redd hede) has been in use since at least 1510. It is associated with fair skin color, lighter eye colors (gray, blue, green, and hazel), freckles, and sensitivity to ultraviolet light.

Cultural reactions have varied from ridicule to admiration; many common stereotypes exist regarding redheads and they are often portrayed as fiery-tempered.

Historical
Several accounts by Greek writers mention redheaded people. A fragment by the poet Xenophanes describes the Thracians as blue-eyed and red haired. Herodotus described the Budini people as being predominantly red haired. Dio Cassius described Boudica, Queen of the Iceni, to be "tall and terrifying in appearance... a great mass of red hair... over her shoulders."

The Roman historian Tacitus commented on the "red hair and large limbs of the inhabitants of Caledonia", which he connected with some red haired Gaulish tribes of Germanic and Belgic relation.

In Asia, red hair has been found among the ancient Tocharians, who occupied the Tarim Basin in what is now the northwesternmost province of China. Caucasian Tarim mummies have been found with red hair dating to the 2nd millennium BC.

Red hair is also found amongst Polynesians, and is especially common in some tribes and family groups. In Polynesian culture red hair has traditionally been seen as a sign of descent from high ranking ancestors and a mark of rulership.

Modern
Today, red hair is most commonly found at the northern and western fringes of Europe; it is associated particularly with the people located in the United Kingdom and in Ireland (although Victorian era ethnographers claimed that the Udmurt people of the Volga were "the most red-headed men in the world"). Redheads are common among Germanic and Celtic peoples.

Redheads constitute approximately 4 percent of the European population. Scotland has the highest proportion of redheads; 13 per cent of the population has red hair and approximately 40 per cent carries the recessive redhead gene. Ireland has the second highest percentage; as many as 10 per cent of the Irish population has red, auburn, or strawberry blond hair. It is thought that up to 46 percent of the Irish population carries the recessive redhead gene. A 1956 study of hair colour amongst British army recruits also found high levels of red hair in Wales and the English Border counties.

Red hair is also fairly common amongst the Ashkenazi Jewish populations, possibly because of the influx of European DNA over a period of centuries, or in the original founding of their communities in Europe, although both Esau and David are described in the Bible as red-haired. In European culture, prior to the 20th century, red hair was often seen as a stereotypically Jewish trait: during the Spanish Inquisition, all those with red hair were identified as Jewish. In Italy, red hair was associated with Italian Jews, and Judas was traditionally depicted as red-haired in Italian and Spanish art. Writers from Shakespeare to Dickens would identify Jewish characters by giving them red hair. The stereotype that red hair is Jewish remains in parts of Eastern Europe and Russia.

In the United States, it is estimated that 2-6% of the population has red hair. This would give the U.S. the largest population of redheads in the world, at 6 to 18 million, compared to approximately 650,000 in Scotland and 420,000  in Ireland.

Red or reddish-tinged hair is also found in other European populations particularly in the Nordic and Baltic countries as well as parts of the Netherlands, Spain, Belgium, France, Greece, Turkey, Portugal, Italy, Germany, Russia and South Slavic countries.

The Berber populations of Morocco and northern Algeria have occasional redheads. Red hair frequency is especially significant among the Kabyles from Algeria, where it reaches 4 percent. The Queen of Morocco, Lalla Salma wife of king Mohammed VI, has red hair. Abd ar-Rahman I also had red hair, his mother being a Christian Berber slave.

In Asia, darker or mixed tinges of red hair can be found sporadically from Northern India, the northern Middle East (such as Iran, Iraq, Syria, Lebanon, Jordan, Israel, Palestine), and in rare instances on the Island of Hirado, Japan and the South Pacific. Red hair can be found amongst those of Iranian descent, such as the Persians, Lurs, Nuristanis and Pashtuns. Emigration from the these people as well as parts of the Middle East, Central Asia, North India, and North Africa added to the population of red-haired humans in the Americas, Australia, New Zealand, South Africa, and other parts of Africa and Europe.

Biochemistry and genetics


The pigment pheomelanin gives red hair its distinctive color. Red hair has far more of the pigment pheomelanin than it has of the dark pigment eumelanin.

The genetics of red hair, discovered in 1997, appear to be associated with the melanocortin-1 receptor (MC1R), which is found on chromosome 16. Red hair is associated with fair skin color because of low concentrations of eumelanin throughout the body of those with red hair. This lower melanin-concentration confers the advantage that a sufficient concentration of important Vitamin D can be produced under low light conditions. However, when UV-radiation is strong (as in regions close to the equator) the lower concentration of melanin leads to several medical disadvantages, such as a higher risk of skin cancer.

The MC1R recessive variant gene that gives people red hair and fair skin is also associated with freckles, though it is not uncommon to see a redhead without freckles. Eighty percent of redheads have an MC1R gene variant, and the prevalence of these alleles is highest in Scotland and Ireland. The alleles that code for red hair occur close to the alleles that affect skin color, so it seems that the phenotypic expression for lighter skin and red hair are interrelated.

Red hair can originate from several different changes on the MC1R-gene. If one of these changes is present on both chromosomes then the respective individual is likely to have red hair. This type of inheritance is described as an autosomal recessive mode of inheritance. Even if both parents do not have red hair themselves, both can be carriers for the gene and have a redheaded child.

Genetics
The alleles Arg151Cys, Arg160Trp, Asp294His, and Arg142His on MC1R are shown to be recessives for the red hair phenotype. The gene HCL2 (also called RHC or RHA) on chromosome 4 may also be related to red hair.

Origins
Red hair is the rarest natural hair color in humans. The pale skin associated with red hair may have been advantageous in far-northern climates where sunlight is scarce. Studies by Bodmer and Cavalli-Sforza (1976) hypothesized that lighter skin pigmentation prevents rickets in colder latitudes by encouraging higher levels of Vitamin D production and also allows the individual to retain heat better than someone with darker skin. In 2000, Harding et al. concluded that red hair was not the result of positive selection and instead proposed that it occurs because of a lack of negative selection. In Africa, for example, red hair is selected against because high levels of sun would be harmful to fair skin. However, in Northern Europe this does not happen, so redheads come about through genetic drift. Rees (2004) suggested that the vividness and rarity of red hair may lead to its becoming desirable in a partner and therefore it could become more common through sexual selection.

Estimates on the original occurrence of the currently active gene for red hair vary from 20,000 to 100,000 years ago.

A DNA study has concluded that some Neanderthals also had red hair, although the mutation responsible for this differs from that which causes red hair in modern humans.

Extinction hoax
A 2007 report in The Courier-Mail, which cited the National Geographic magazine and unnamed "geneticists", said that red hair is likely to die out in the near future. Other blogs and news sources ran similar stories that attributed the research to the magazine or the "Oxford Hair Foundation". However, a HowStuffWorks article says that the foundation was funded by hair-dye maker Procter & Gamble, and that other experts had dismissed the research as either lacking in evidence or simply bogus. The National Geographic article in fact states "while redheads may decline, the potential for red isn't going away".

Red hair is caused by a relatively rare recessive gene, the expression of which can skip generations. It is not likely to disappear at any time in the foreseeable future.

Melanoma
Melanin in the skin aids UV tolerance through suntanning, but fair-skinned persons lack the levels of melanin needed to prevent UV-induced DNA-damage. Studies have shown that red hair alleles in MC1R increase freckling and decrease tanning ability. It has been found that Europeans who are heterozygous for red hair exhibit increased sensitivity to UV radiation.

Red hair and its relationship to UV sensitivity are of interest to many melanoma researchers. Sunshine can both be good and bad for a person's health and the different alleles on MC1R represent these adaptations. It also has been shown that individuals with pale skin are highly susceptible to a variety of skin cancers such as melanoma, basal cell carcinoma, and squamous cell carcinoma.

Pain tolerance and injury
Two studies have demonstrated that people with red hair have different sensitivity to pain compared to people with other hair colors. One study found that people with red hair are more sensitive to thermal pain (associated with naturally occurring low vitamin K levels), while another study concluded that redheads are less sensitive to pain from multiple modalities, including noxious stimuli such as electrically induced pain.

Researchers have found that people with red hair require greater amounts of anesthetic. Other research publications have concluded that women with naturally red hair require less of the painkiller pentazocine than do either women of other hair colors or men of any hair color. A study showed women with red hair had a greater analgesic response to that particular pain medication than men. A follow-up study by the same group showed that men and women with red hair had a greater analgesic response to morphine-6-glucuronide.

The unexpected relationship of hair color to pain tolerance appears to be because redheads have a mutation in a hormone receptor that can apparently respond to at least two different hormones: the skin pigmentation hormone melanocyte-stimulating hormone, and the pain relieving hormone known as endorphins. (These hormones are both derived from the same precursor molecule, POMC, and are structurally similar.) Specifically, redheads have a mutated MC1R gene, which produces a mutated MC1R receptor, also known as the melanocortin-1 receptor. Melanocytes, which are cells that produce pigment in skin and hair, use the MC1R receptor to recognize and respond to melanocyte-stimulating hormone from the anterior pituitary gland. Melanocyte-stimulating hormone normally stimulates melanocytes to make black eumelanin, but if the melanocytes have a mutated MC1R receptor, they will make reddish pheomelanin instead. The MC1R receptor also occurs in the brain, where it is one of a large set of POMC-related receptors that are apparently involved not only in responding to MSH, but also in responses to endorphins and possibly other POMC-derived hormones. Though the details are not clearly understood, it appears that there is some "cross talk" between the POMC hormones that may explain the link between red hair and pain tolerance.

There is little or no evidence to support the belief that people with red hair have a higher chance than people with other hair colors to hemorrhage or suffer other bleeding complications. One study, however, reports a link between red hair and a higher rate of bruising.

Red hair of pathological origin
Most red hair is caused by the MC1R gene and is non-pathological. However, in rare cases red hair can be associated with disease or genetic disorder:
 * In cases of severe malnutrition, normally dark human hair may turn red or blonde. The condition, part of a syndrome known as kwashiorkor, is a sign of critical starvation caused chiefly by protein deficiency, and is common during periods of famine.
 * One variety of albinism (Type 3, aka rufous albinism), sometimes seen in Africans and inhabitants of New Guinea, results in red hair and red-colored skin.
 * Red hair is found on people lacking pro-opiomelanocortin.

Culture


In various times and cultures, red hair has been prized, feared, and ridiculed.

Beliefs about temperament
A common belief about redheads is that they have fiery tempers and sharp tongues. In Anne of Green Gables, a character says of Anne Shirley, the redheaded heroine, that "her temper matches her hair", while in The Catcher in the Rye, Holden Caulfield remarks that "People with red hair are supposed to get mad very easily, but Allie [his dead brother] never did, and he had very red hair."

During the early stages of modern medicine, red hair was thought to be a sign of a sanguine temperament. In the Indian medicinal practice of Ayurveda, redheads are seen as most likely to have a Pitta temperament.

Another belief is that redheads are highly sexed; for example, Jonathan Swift satirizes redhead stereotypes in part four of Gulliver's Travels, "A Voyage to the Country of the Houyhnhnms," when he writes that: "It is observed that the red-haired of both sexes are more libidinous and mischievous than the rest, whom yet they much exceed in strength and activity." Swift goes on to write that: "...neither was the hair of this brute [a Yahoo] of a red color (which might have been some excuse for an appetite a little irregular) but black as a sloe..." In the novel and film Red-Headed Woman, the titular protagonist is a sexually aggressive home-wrecker who frequently throws violent temper tantrums.

Fashion and art


Queen Elizabeth I of England was a redhead, and during the Elizabethan era in England, red hair was fashionable for women. In modern times, red hair is subject to fashion trends; celebrities such as Nicole Kidman, Alyson Hannigan, Marcia Cross, Christina Hendricks and Geri Halliwell can boost sales of red hair dye.

Sometimes, red hair darkens as people get older, becoming a more brownish color or losing some of its vividness. This leads some to associate red hair with youthfulness, a quality that is generally considered desirable. In several countries such as India, Iran, Bangladesh and Pakistan, henna and saffron are used on hair to give it a bright red appearance.

Many painters have exhibited a fascination with red hair. The color "titian" takes its name from Titian, who often painted women with red hair. Early Renaissance artist Sandro Botticelli's famous painting The Birth of Venus depicts the mythological goddess Venus as a redhead. Other painters notable for their redheads include the Pre-Raphaelites, Edmund Leighton, Modigliani, and Gustav Klimt.

Sir Arthur Conan Doyle's story The Red-Headed League involves a man who is asked to become a member of a mysterious group of red-headed people. The 1943 film DuBarry Was a Lady featured red-heads Lucille Ball and Red Skelton in Technicolor.

Medieval beliefs


Red hair was thought to be a mark of a beastly sexual desire and moral degeneration. A savage red-haired man is portrayed in the fable by Grimm brothers (Der Eisenhans) as the spirit of the forest of iron. Theophilus Presbyter describes how the blood of a red-haired young man is necessary to create gold from copper, in a mixture with the ashes of a basilisk.

Montague Summers, in his translation of the Malleus Maleficarum, notes that red hair and green eyes were thought to be the sign of a witch, a werewolf or a vampire during the Middle Ages;

"Those whose hair is red, of a certain peculiar shade, are unmistakably vampires. It is significant that in ancient Egypt, as Manetho tells us, human sacrifices were offered at the grave of Osiris, and the victims were red-haired men who were burned, their ashes being scattered far and wide by winnowing-fans. It is held by some authorities that this was done to fertilize the fields and produce a bounteous harvest, red-hair symbolizing the golden wealth of the corn. But these men were called Typhonians, and were representatives not of Osiris but of his evil rival Typhon, whose hair was red."

Modern-day discrimination
In Britain, it has been speculated that the dislike of red hair may derive from the historical English sentiment that people of Irish or Celtic background, with a greater prevalence of red hair, were ethnically inferior.

In his book "I Say No" Wilkie Collins (1885) wrote "The prejudice against habitual silence, among the lower order of the people, is almost as inveterate as the prejudice against red hair."

In modern-day UK, the words "ginger" or "ginga" are sometimes derogatorily used to describe red-headed people ("ginger" is not often considered insulting; the abbreviation "ginge" is much more commonly used derogatorily), with terms such as "gingerphobia" (hatred towards redheads) or "gingerism" (prejudice against redheads) used by the British media. In Britain, redheads are also sometimes referred to disparagingly as "carrot tops" and "carrot heads". (The comedian "Carrot Top" uses this stage name.) "Gingerism" has been compared to racism, although this is widely disputed, and bodies such as the UK Commission for Racial Equality do not monitor cases of discrimination and hate crimes against redheads. A UK woman recently won an award from a tribunal after being sexually harassed and receiving abuse because of her red hair; a family in Newcastle upon Tyne, England, was forced to move twice after being targeted for abuse and hate crime on account of their red hair; and in 2003, a 20 year old was stabbed in the back for "being ginger". In May 2009, a British schoolboy committed suicide after being bullied for having red hair. The British singer Mick Hucknall, who believes that he has repeatedly faced prejudice or been described as ugly on account of his hair color, argues that Gingerism should be described as a form of racism.

This prejudice has been satirised on a number of TV shows. The British comedian Catherine Tate (herself a redhead) appeared as a red-haired character in a running sketch of her series The Catherine Tate Show. The sketch saw fictional character Sandra Kemp, who was forced to seek solace in a refuge for ginger people because they had been ostracised from society. The British comedy Bo' Selecta! (starring redhead Leigh Francis) featured a spoof documentary which involved a caricature of Mick Hucknall presenting a show in which celebrities (played by themselves) dyed their hair red for a day and went about daily life being insulted by people. The pejorative use of the word "ginger" and related discrimination was used to illustrate a point about racism and prejudice in the "Ginger Kids", "Le Petit Tourette", "It's a Jersey Thing" and "Fatbeard" episodes of South Park.

In America, film and television programmes often portray school bullies as having red hair; for example, Scut Farkus from A Christmas Story or the O'Doyle family in the movie Billy Madison. The bully character Caruso in Everybody Hates Chris is a redhead. However, children with red hair are often themselves targeted by bullies; "Somebody with ginger hair will stand out from the crowd," says anti-bullying expert Louise Burfitt-Dons.

In Australian slang, redheads are often referred to as rangas (a word derived from the red-haired ape, the orangutan), sometimes with derogatory connotations.

In November 2008 social networking website Facebook received criticism after a 'Kick a Ginger' group, which aimed to establish a "National Kick a Ginger Day" on November 20, acquired almost 5,000 members. A 14-year-old boy from Vancouver who ran the Facebook group was subjected to an investigation by the Royal Canadian Mounted Police for possible hate crimes.

In December 2009 British supermarket chain Tesco was forced to withdraw a Christmas card which had the image of a child with red hair sitting on the lap of Santa Claus, and the words: "Santa loves all kids. Even ginger ones" after customers complained the card was too offensive.

In October 2010, Harriet Harman, the former Equality Minister in the British government under Labour, faced accusations of prejudice, after she described the red-haired Treasury secretary Danny Alexander as a "ginger rodent". Alexander responded to the insult by stating that he was "proud to be ginger". Harman was subsequently forced to apologise for the comment, after facing criticism for prejudice against a minority group.

In September 2011, Cryos International, one of the world's largest sperm banks, announced that it would no longer accept donations from red-haired men due to low demand from women seeking artificial insemination.

Use of term in East Asia to refer to ethnic European people
The term ang mo in Hokkien (Min Nan) Chinese means "red-haired", and is used in Malaysia and Singapore to refer to white people. The epithet is sometimes rendered as ang mo kui (红毛鬼) meaning "red-haired devil", similar to the Cantonese term gweilo ("foreign devil"). Thus it is viewed as racist and derogatory by some Caucasians. Others, however, maintain it is acceptable. Despite this ambiguity, it is a widely used term. It appears, for instance, in Singaporean newspapers such as The Straits Times, and in television programmes and films.

The Chinese characters for ang mo are the same as those in the historical Japanese term Kōmō (紅毛), which was used during the Edo period (1603–1868) as an epithet for (northwestern European) white people. It primarily referred to Dutch traders who were the only Europeans allowed to trade with Japan during Sakoku, its 200-year period of isolation. See, for example, ; ; ; ; ;

Red hair festival


Redheadday is the name of a Dutch festival that takes place each first weekend of September in the city of Breda, the Netherlands. The two-day festival is a gathering of people with natural red hair, but is also focused on art related to the color red. Activities during the festival include lectures, workshops and demonstrations.

Religious and mythological traditions
In the Iliad, Achilles' hair is described as ξανθῆς, usually translated as blonde, or golden but sometimes as red or tawny. His son Neoptolemus also bears the name Pyrrhus, a possible reference to his own red hair.

The Norse god Thor is usually described as having red hair.



Esau's entire body is supposed to have been covered with red hair. King David is also known for having red hair, based on the description of his physical appearance as admoni, the Biblical Hebrew word normally interpreted to mean "ruddy", or "red-haired".

Early artistic representations of Mary Magdalene usually depict her as having long flowing red hair, although a description of her hair color was never mentioned in the Bible, and it is possible the color is an effect caused by pigment degradation in the ancient paint.

Red is the preferred dyeing color in Islam. It is said that Muhammad used to dye his hair red.

Judas Iscariot is also represented with red hair in Spanish culture  and in the works of William Shakespeare, reinforcing the negative stereotype. In Spain the prejudice is extended to so-colored cats and dogs.

There is a tradition amongst astrologers that the planet Mars ("the red planet") is more likely to be rising above the eastern horizon (on or near the astrological Ascendant, which supposedly influences a person's appearance) at the time of the birth of a red haired person than for the population in general.