CA8

Carbonic anhydrase-related protein is an is_associated_with::enzyme that in humans is encoded by the CA8 is_associated_with::gene.

Function
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.

Interactions
CA8 has been shown to interact with is_associated_with::ITPR1.