GPRC5A

Retinoic acid-induced protein 3 is a is_associated_with::protein that in humans is encoded by the GPRC5A is_associated_with::gene.

Function
This gene encodes a member of the type 3 is_associated_with::G protein-coupled receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between is_associated_with::retinoic acid and is_associated_with::G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.

Post transcriptional regulation
GPRC5A is one of only a handful of genes known in the literature that are post-transcriptionally controlled by is_associated_with::miRNAs through their is_associated_with::5'UTR.

Clinical Significance
GPRC5A is dysregulated in many human cancers and in other diseases.