CCL4

Chemokine (C-C motif) ligand 4, also known as CCL4, is a is_associated_with::protein which in humans is encoded by the CCL4 is_associated_with::gene.

Function
CCL4, also known as is_associated_with::Macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for is_associated_with::CCR5 receptors. It is a is_associated_with::chemoattractant for is_associated_with::natural killer cells, is_associated_with::monocytes and a variety of other immune cells.

CCL4 is a major HIV-suppressive factor produced by CD8+ T cells.

is_associated_with::Perforin-low memory CD8+ T cells that normally synthesize MIP-1-beta.

Interactions
CCL4 has been shown to interact with is_associated_with::CCL3.