Rs1800860

rs1800860 is a SNP in the RET ret proto-oncogene.

A study of newborns concluded that Caucasian newborns who were clinically normal and carried a rs1800860(A) allele had kidney volumes 10% smaller and cord blood cystatin C levels 9% higher than those with the rs1800860(G;G) genotype. Since individuals with lower nephron numbers have an increased lifetime risk for essential hypertension or renal insufficiency, this may have clinical consequences in adult life (but this remains to be proven).