Rs1805097

rs1805097, also known as Gly1057Asp, is a SNP in the insulin receptor substrate-2 IRS2 gene. The rs1805097(G) allele is associated with the Gly, and the (A) allele with Asp.

A longevity study categorizing 677 participants as either long-lived (i.e. over 85 years old) or not (less than 85) somehow concluded that rs1805097(A;A) individuals were about twice as likely to reach extreme old age (odds ratio 2.03, CI:1.39-2.99, p = .0003).