GBA2

Non-lysosomal glucosylceramidase is an is_associated_with::enzyme that in humans is encoded by the GBA2 is_associated_with::gene. It has is_associated_with::glucosylceramidase activity.

Function
This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.