MST4

Serine/threonine protein kinase MST4, also known as mammalian STE20-like protein kinase 4 (MST-4), is a is_associated_with::protein that in humans is encoded by the MST4 is_associated_with::gene.

Function
The product of this gene is a member of the GCK group III family of is_associated_with::kinases, which are a subset of the is_associated_with::Ste20-like kinases. The encoded protein contains an is_associated_with::amino-terminal kinase domain, and a is_associated_with::carboxy-terminal regulatory domain that mediates is_associated_with::homodimerization. The protein kinase localizes to the is_associated_with::Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by is_associated_with::caspase-3 in vitro, and may function in the is_associated_with::apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Interactions
RP6-213H19.1 has been shown to interact with:
 * is_associated_with::CTTNBP2NL,
 * is_associated_with::CTTNBP2,
 * is_associated_with::FAM40A,
 * is_associated_with::MOBKL3,
 * is_associated_with::PDCD10,
 * is_associated_with::STRN3, and
 * is_associated_with::STRN.