TBC1D10A

TBC1 domain family member 10A is a is_associated_with::protein that in humans is encoded by the TBC1D10A is_associated_with::gene.

Model organisms
is_associated_with::Model organisms have been used in the study of TBC1D10A function. A conditional is_associated_with::knockout mouse line, called Tbc1d10atm2a(EUCOMM)Wtsi was generated as part of the is_associated_with::International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists — at the is_associated_with::Wellcome Trust Sanger Institute. Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Twenty three tests were carried out and one significant is_associated_with::phenotype was reported. is_associated_with::Homozygous is_associated_with::mutant male adults had abnormal is_associated_with::clinical chemistry, including decreased circulating is_associated_with::LDL cholesterol, is_associated_with::alanine transaminase and is_associated_with::alkaline phosphatase levels.