Cytochrome b5, type A

Cytochrome b5, form A (gene name CYB5A), is a human is_associated_with::microsomal is_associated_with::cytochrome b5.

Cytochrome b5 is a membrane bound is_associated_with::hemoprotein which function as an electron carrier for several membrane bound is_associated_with::oxygenases. It has two isoforms produced by is_associated_with::alternative splicing. Isoform 1 is bound to the cytoplasmic side of the is_associated_with::endoplasmic reticulum. It has a C-terminal transmembrane alpha-helix. Isoform 2 was found in cytoplasm. Defects in CYB5A are the cause of type IV hereditary is_associated_with::methemoglobinemia.