NEUROD1

Neurogenic differentiation 1 (NeuroD1), also called β2, is a is_associated_with::transcription factor of the is_associated_with::NeuroD-type. It is encoded by the human gene NEUROD1.

It is a member of the NeuroD family of is_associated_with::basic helix-loop-helix (bHLH) is_associated_with::transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the is_associated_with::insulin gene, and mutations in this gene result in is_associated_with::type II diabetes mellitus.

Interactions
NEUROD1 has been shown to interact with is_associated_with::MAP3K10, MAFA and is_associated_with::Cyclin D1.