FANCE

Fanconi anemia group E protein is a is_associated_with::protein that in humans is encoded by the FANCE is_associated_with::gene.

Function
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E.

Interactions
FANCE has been shown to interact with:
 * is_associated_with::FANCA,
 * is_associated_with::FANCD2,
 * is_associated_with::FANCF
 * is_associated_with::FANCG,  and
 * FANCC.