CHMP5

Charged multivesicular body protein 5 is a is_associated_with::protein that in humans is encoded by the CHMP5 is_associated_with::gene.

Function
CHMP5 belongs to the is_associated_with::chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of is_associated_with::ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, is_associated_with::CHMP1A, is required for both MVB formation and regulation of is_associated_with::cell cycle progression.