Rs2076756

rs2076756 is a SNP of the NOD2 gene found in a genome-wide association study to be associated with Crohn's disease.

In several European populations, the minor NOD2 allele, rs2076756(G), is associated with increased risk for Crohn's disease. The odds ratio (pooled over several populations) is 1.71 (CI: 1.42-2.05, p=6x10-8).

Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway.

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.

Strategies and issues in the detection of pathway enrichment in genome-wide association studies.

Detecting gene-gene interactions that underlie human diseases.

Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology.