NOBOX

Homeobox protein NOBOX, also known as newborn ovary homeobox protein, is a is_associated_with::protein that in humans is encoded by the NOBOX is_associated_with::gene.

Function
NOBOX is a is_associated_with::homeobox gene that is preferentially expressed in is_associated_with::oocytes. In mice, it is essential for is_associated_with::folliculogenesis and regulation of oocyte-specific genes.

Clinical significance
A mutation in the NOBOX gene is associated with is_associated_with::premature ovarian failure.