CLASP1

Cytoplasmic linker associated protein 1, also known as CLASP1, is a is_associated_with::protein which in humans is encoded by the CLASP1 is_associated_with::gene.

Function
CLASP1 belongs to a family of is_associated_with::microtubule-associated proteins involved in attachment of is_associated_with::microtubules to the is_associated_with::cell cortex in animals and plants. CLASPs, such as CLASP1, interact with CLIPs (e.g., is_associated_with::CLIP1). In animal cells, CLASP1 is involved in the regulation of microtubule dynamics at the is_associated_with::kinetochore and throughout the spindle. CLASP1 controls the interactions of astral microtubules with the cell cortex in mitosis, which is important for the proper positioning and orientation of the spindle.