Arylsulfatase E

Arylsulfatase E, also known as ARSE, is an enzyme that, in humans, is encoded by the ARSE is_associated_with::gene.

Function
Arylsulfatase E is a member of the is_associated_with::arylsulfatase subfamily of is_associated_with::sulfatase enzymes that catalyze the hydrolysis of sulfate esters. It is glycosylated postranslationally and localized to the is_associated_with::golgi apparatus. Sulfatases are essential for the correct composition of bone and cartilage matrix.

Clinical significance
Deficiencies in ARSE are associated with is_associated_with::X-linked recessive chondrodysplasia punctata, a disease characterized by abnormalities in cartilage and bone development.