TAS2R16

TAS2R16 (is_associated_with::taste receptor, type 2, member 16) is a is_associated_with::human is_associated_with::gene that encodes for a receptor that may play a role in the perception of bitterness.

The TAS2R16 gene is located on the long (q) arm of chromosome 7 at position 31.1 - 31.3, from is_associated_with::base pair 122,228,764 to base pair 122,229,639.

Clinical significance
Variants of this gene have been linked to an increased risk for is_associated_with::alcohol dependence.

There is an East African origin for high is_associated_with::salicin sensitivity, and thus sensitivity to bitterness in people from this region, with this phenotype matched to TAS2R16 variants.