MATR3

Matrin-3 is a is_associated_with::protein that in humans is encoded by the MATR3 is_associated_with::gene.

Function
The protein encoded by this gene is localized in the is_associated_with::nuclear matrix. It may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. Two transcript variants encoding the same protein have been identified for this gene.

Pathology
Mutations in the Matrin 3 gene are associated with familial is_associated_with::amyotrophic lateral sclerosis.