COX8A

Cytochrome c oxidase subunit 8A is a is_associated_with::protein that in humans is encoded by the COX8A is_associated_with::gene. Cytochrome c oxidase 8A is a subunit of the is_associated_with::cytochrome c oxidase complex, also known as is_associated_with::Complex IV.

Structure
COX8A is a 7.6 kDa protein composed of 69 amino acids. This gene encodes the nuclear-encoded subunit 8A of the human mitochondrial respiratory chain enzyme complex cytochrome c oxidase. The complex consists of 13 mitochondrial- and nuclear-encoded subunits.

Function
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton is_associated_with::electrochemical gradient across the inner mitochondrial membrane. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex.