Wee1-like protein kinase

WEE1 homolog (S. pombe), also known as WEE1, is a is_associated_with::protein which in humans is encoded by the WEE1 is_associated_with::gene.

Function
This gene encodes a nuclear protein, which is a is_associated_with::tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine is_associated_with::phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between is_associated_with::DNA replication and is_associated_with::mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

Interactions
Wee1-like protein kinase has been shown to interact with is_associated_with::YWHAB and is_associated_with::PIN1.