RSPH6A

Radial spoke head protein 6 homolog A (RSPH6A) also known as radial spoke head-like protein 1 (RSHL1) is a is_associated_with::protein that in humans is encoded by the RSPH6A is_associated_with::gene.

Function
Radial spoke head protein 6 homolog A is similar to a sea urchin is_associated_with::radial spoke head protein. Radial spoke protein complexes form part of the is_associated_with::axoneme of eukaryotic is_associated_with::flagella and are located between the axoneme's outer ring of doublet is_associated_with::microtubules and central pair of microtubules. In is_associated_with::Chlamydomonas, radial spoke proteins are thought to regulate the activity of is_associated_with::dynein and the symmetry of flagellar bending patterns.

Clinical significance
The RSPH6A gene maps to a region of chromosome 19 that is linked to primary ciliary dyskinesia-2 (CILD2).