Cyclin K

Cyclin-K is a is_associated_with::protein that in humans is encoded by the CCNK is_associated_with::gene.

Function
The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.

Interactions
Cyclin K has been shown to interact with is_associated_with::CDK9. Cyclin K also interacts with HIV nef protein.