Rs1859345

rs1859345 is a SNP in the - get ready - "sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1" SPOCK1 gene.

A study of 477 Caucasian women, followed up by replication studies in another ~1,600 and also 1,300+ Chinese women, found that several linked SNPs in the SPOCK1 gene are associated with age at menarche. rs1859345 replicated across all groups studied (p < 10e-3), with the minor (C) allele associated with a (slightly) earlier age at menarche.