Rs2569190

rs2569190, also known as C260T, is a SNP in the CD14 gene.

rs2569190(C) (frequency = 39%) increased stroke risk among smokers (OR = 2.05, 95% CI=1.09-3.86, p=0.03), but not among non-smokers (OR = 0.93, 95% CI=0.62-1.39, p=0.72)

rs1295685 and rs20541 were significantly associated with elevated IgE levels in pooled analyses. rs2569190(T;T) and rs2569191(C;C) genotypes associated with lower IgE

A meta-analysis of 7 studies (comprising a total of 1488 patients and 1600 control subjects) found no significant association between rs2569190 and cerebrovascular diseases.