Familial dysbetalipoproteinemia

Familial dysbetalipoproteinemia (also known as "Broad beta disease" and "Remnant removal disease" ) is a condition characterized by increased LDL, triglyceride, and cholesterol levels, and decreased HDL levels. The condition is caused by a deficiency in apolipoprotein E that serves as a ligand for chylomicron and IDL receptors in the liver: The normal ApoE turns into the defective ApoE2 form.