HEAT repeat domain

The HEAT repeat domain is a protein domain found in a number of cytoplasmic proteins including the four that the give rise to the acronym HEAT ( H untingtin, elongation factor 3 ( E F3), protein phosphatase 2A (PP2 A ), and the yeast PI3-kinase T OR1). HEAT repeats form a rod-like helical structures which are involved in intracellular transport.