CD49d

CD49d is an is_associated_with::integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor.

Function
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.

Interactions
CD49d has been shown to interact with is_associated_with::LGALS8 and is_associated_with::Paxillin.