RAD52

RAD52 homolog (S. cerevisiae), also known as RAD52, is a is_associated_with::protein which in humans is encoded by the RAD52 is_associated_with::gene.

Function
The protein encoded by this gene shares similarity with is_associated_with::Saccharomyces cerevisiae Rad52, a is_associated_with::protein important for is_associated_with::DNA double-strand break repair and is_associated_with::homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein is_associated_with::RAD51, which suggested its role in RAD51-related DNA recombination and repair.

Interactions
RAD52 has been shown to interact with RAD51. The Rad52 will ease the loading of Rad51 on ssDNA by interfering with the RPA protein.