CDCA5

Sororin is a is_associated_with::protein that in humans is encoded by the CDCA5 is_associated_with::gene.

Function
Sororin is required for stable binding of is_associated_with::cohesin to is_associated_with::chromatin and for is_associated_with::sister chromatid cohesion in is_associated_with::interphase.

Clinical Significance
Transactivation of Sororin and its phosphorylation at Ser209 by ERK play an important role in is_associated_with::lung cancer proliferation.