Adrenal ferredoxin

Adrenal ferredoxin also known as adrenodoxin or adrenodoxin, mitochondrial or hepatoredoxin or ferredoxin-1 (FDX1) is a is_associated_with::protein that in humans is encoded by the FDX1 is_associated_with::gene. In addition to the expressed gene at this chromosomal locus (11q22), there are pseudogenes located on chromosomes 20 and 21.

Function
Ferredoxin-1 is a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to a terminal is_associated_with::cytochrome P450. This particular oxidation/reduction system is found in steroidogenic tissues, and is involved with the synthesis of is_associated_with::bile acid and is_associated_with::vitamin D. Ferredoxin-1 has been identified in a number of different tissues but all forms have been shown to be identical and are not tissue specific.