CTTNBP2

Cortactin-binding protein 2 is a is_associated_with::protein that in humans is encoded by the CTTNBP2 is_associated_with::gene.

Function
This gene encodes a protein with six ankyrin repeats and several proline-rich regions. A similar gene in rat interacts with a central regulator of the actin cytoskeleton.

Interactions
CTTNBP2 has been shown to interact with:
 * is_associated_with::MOBKL3,
 * is_associated_with::PPP2CA,
 * is_associated_with::RP6-213H19.1,
 * is_associated_with::STRN3, and
 * is_associated_with::STRN.

Model organisms
is_associated_with::Model organisms have been used in the study of CTTNBP2 function. A conditional is_associated_with::knockout mouse line called Cttnbp2tm1b(KOMP)Wtsi was generated at the is_associated_with::Wellcome Trust Sanger Institute. Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping