IL1RAPL1

X-linked interleukin-1 receptor accessory protein-like 1 is a is_associated_with::protein that in humans is encoded by the IL1RAPL1 is_associated_with::gene.

Function
The protein encoded by this gene is a member of the is_associated_with::interleukin-1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (is_associated_with::IL1RAPL2).

Clinical significance
This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic is_associated_with::mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the is_associated_with::hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.