SEC16B

Protein transport protein Sec16B is a is_associated_with::protein that in humans is encoded by the SEC16B is_associated_with::gene.

Model organisms
is_associated_with::Model organisms have been used in the study of SEC16B function. A conditional is_associated_with::knockout mouse line, called Sec16btm1a(KOMP)Wtsi was generated as part of the is_associated_with::International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.

Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Twenty one tests were carried out on is_associated_with::mutant mice and one significant abnormality was observed: is_associated_with::homozygote mutants had decreased circulating is_associated_with::cholesterol levels.