CLCNKB

Chloride channel Kb, also known as CLCNKB, is a is_associated_with::protein which in humans is encoded by the CLCNKB is_associated_with::gene.

Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated is_associated_with::chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III is_associated_with::Bartter syndrome. is_associated_with::CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.