Hallermann–Streiff syndrome

Hallermann-Streiff syndrome (also known as the François Dyscephalic Syndrome, Hallermann-Streiff-François syndrome, Oculomandibulodyscephaly with hypotrichosis and Oculomandibulofacial syndrome) is a congenital disorder that affects growth, cranial development, hair growth and dental development.

There are fewer than 200 people with the syndrome worldwide. An organisation supporting people with the Hallermann Streiff Syndrome is the Germany based "Schattenkinder e.V."

Presentation
Patients with this syndrome are shorter than the average person and may not develop hair in many places, including in the facial, leg and pubic areas. Patients also have eye problems including clouded eyes or reduced eye size, bilateral cataracts and glaucoma.

It can be associated with sleep apnea.

It can complicate intubation.

Genetics
It may be associated with GJA1.

Eponym
It is named for Wilhelm Hallermann and Enrico Streiff.