SOX18

Transcription factor SOX-18 is a is_associated_with::protein that in humans is encoded by the SOX18 is_associated_with::gene.

Function
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of is_associated_with::hypotrichosis-is_associated_with::lymphedema-is_associated_with::telangiectasia.

Interactions
SOX18 has been shown to interact with is_associated_with::MEF2C.