IFT88

Intraflagellar transport protein 88 homolog is a is_associated_with::protein that in humans is encoded by the IFT88 is_associated_with::gene.

Function
This gene encodes a member of the tetratrico peptide repeat (TPR) family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene. In 2012 a mutation was found to be responsible for a novel form of is_associated_with::ciliopathy and is_associated_with::anosmia in humans capable of remedy in mice by adenoviral mediated is_associated_with::gene therapy.

Interactions
IFT88 has been shown to interact with is_associated_with::BAT2.