CHST11

Carbohydrate sulfotransferase 11 is an is_associated_with::enzyme that in humans is encoded by the CHST11 is_associated_with::gene.

Clinical relevance
Mutations in this gene have been associated to susceptibility for osteoarthritis.

Model organisms
is_associated_with::Model organisms have been used in the study of CHST11 function. A conditional is_associated_with::knockout mouse line called Chst11tm1a(KOMP)Wtsi was generated at the is_associated_with::Wellcome Trust Sanger Institute. Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping - in-depth bone and cartilage phenotyping

''