BIRC6

Baculoviral IAP repeat-containing protein 6 is a is_associated_with::protein that in humans is encoded by the BIRC6 is_associated_with::gene.

Function
This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination.

Interactions
BIRC6 has been shown to interact with is_associated_with::KIF23.

Diseases
BIRC6 is implicated in leukemia, melanoma, breast cancer, lung cancer, colorectal cancer, and other cancers (see the is_associated_with::Atlas of Genetics and Cytogenetics in Oncology and Haematology, ).