Lefty

Lefty may refer to:
 * left-handedness
 * A nickname for a person who is left-handed or an adherent of left-wing politics
 * The Tale of Cross-eyed Lefty from Tula and the Steel Flea by Leskov
 * Lefty (1964 film), an animated film by Ivan Ivanov-Vano
 * Lefty (1986 film)
 * Lefty (ballet)
 * Lefty, a super computer used at Cornell University for research on South Korean products
 * Lefty the Salesman, a Sesame Street character
 * Lefty shock, a front shock on some Cannondale bicycle wheels
 * Lefty, a 1988 album by Art Garfunkel
 * "Lefty", a song by Soft Machine from the album Six
 * LEFTY, Vernon/Kelowna, BC, Canada Rock Band
 * Lefty, proteins that are closely related members of the TGF-beta family of growth factors

People with the nickname

 * Lefty (rapper), American rapper also known as The L.E.F.T., born Paul DeLisle
 * Lefty Atkinson, professional baseball pitcher
 * Lefty Bates, blues guitarist
 * Lefty Bertrand, professional baseball pitcher
 * Lefty Clarke, professional baseball pitcher
 * Lefty Dizz, Chicago blues guitarist and singer
 * Lefty Driesell, college basketball coach
 * Lefty Frizzell, country music performer
 * Lefty Gomez, Mexican-American professional baseball pitcher
 * Lefty Grove, professional baseball pitcher
 * Lefty O'Doul, professional baseball player and manager
 * Lefty Rosenthal, sports handicapper
 * Lefty Lew Tendler, Hall of Fame bantamweight, lightweight, and welterweight boxer
 * Steve Carlton, professional baseball pitcher
 * Cliff Chambers, professional baseball pitcher
 * Phil Mickelson, professional golfer
 * Benjamin Ruggiero, mobster
 * Gaius Mucius Scaevola, brave Roman youth