AKAP11

A-kinase anchor protein 11 is an is_associated_with::enzyme that in humans is encoded by the AKAP11 is_associated_with::gene.

Function
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of is_associated_with::protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout is_associated_with::spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function.

Interactions
AKAP11 has been shown to interact with:
 * is_associated_with::GSK3B,
 * is_associated_with::PPP1CA,
 * is_associated_with::PRKAR2A,  and
 * is_associated_with::PRKAR2B.