NLRP7

NACHT, LRR and PYD domains-containing protein 7 is a is_associated_with::protein that in humans is encoded by the NLRP7 is_associated_with::gene.

Function
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP7, have an N-terminal pyrin (is_associated_with::MEFV) domain (PYD), followed by a is_associated_with::NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NALPs are implicated in the activation of proinflammatory is_associated_with::caspases (e.g., is_associated_with::CASP1) via their involvement in multiprotein complexes called is_associated_with::inflammasomes.