ID2

DNA-binding protein inhibitor ID-2 is a is_associated_with::protein that in humans is encoded by the ID2 is_associated_with::gene.

Function
The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene.

Interactions
ID2 has been shown to interact with is_associated_with::MyoD and is_associated_with::NEDD9.