HMGA1

High-mobility group protein HMG-I/HMG-Y is a is_associated_with::protein that in humans is encoded by the HMGA1 is_associated_with::gene.

Mice lacking their variant of HMGA1, i.e., Hmga1-/- mice, are is_associated_with::diabetic, show a cardiac hypertrophy and express low levels of the is_associated_with::insulin receptor.

Interactions
HMGA1 has been shown to interact with is_associated_with::CEBPB and is_associated_with::Sp1 transcription factor.