PSCA (gene)

Prostate stem cell antigen is a is_associated_with::protein that in humans is encoded by the PSCA is_associated_with::gene.

This gene encodes a glycosylphosphatidylinositol-anchored cell membrane is_associated_with::glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene has a nonsynonymous nucleotide polymorphism at its start codon.

Clinical significance
This gene is up-regulated in a large proportion of is_associated_with::prostate cancers and is also detected in cancers of the bladder and pancreas.