PLD3

Phospholipase D family, member 3 is a is_associated_with::protein that in humans is encoded by the PLD3 is_associated_with::gene.

Function
This gene encodes a member of the is_associated_with::phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane is_associated_with::phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of is_associated_with::amyloid-beta precursor protein. Mutations in this gene are associated with is_associated_with::Alzheimer disease risk.