Rs2070744

The NOS3 gene encodes nitric oxide synthase 3, and is also known as eNOS; rs2070744 is a SNP in the promoter region that is associated with higher levels of the corresponding mRNA (and possibly protein).

Associations for the risk allele (C) of this SNP include:


 * Rheumatoid Arthritis, and,
 * cardiovascular mortality in high-risk patients
 * Progression (but not occurence) of prostate cancer

Men who carry the C allele responded more favorably to the antihypertensive effects of aerobic exercise

Current HapMap data for this SNP appears wrong (ss42994451). The population diversity information is instead being estimated based on ss48295994 P1, and should be replaced what a new HapMap ss# is available.