Rs4359

This SNP in the ACE gene, also known as C17888T, is reported to influence how quickly African Americans respond to the anti-hypertensive drug ramipril. rs4359(C;C) and rs4359(T;T) homozygotes are able to reach lower blood pressure levels upon treatment with ramipril sooner than rs4359(C;T) heterozygotes. The odds ratio reported for this study, comparing both homozygotes to heterozygotes, is 1.49 (CI: 1.01-2.13).