Neurotensin receptor

The neurotensin receptors are transmembrane receptors that bind the neurotransmitter neurotensin. Two of the receptors encoded by the and  genes contain seven transmembrane helices and are G protein coupled. The third receptor has a single transmembrane domain and is encoded by the gene.

Agonists

 * Peptide
 * Beta-lactotensin (NTS2)
 * JMV-449
 * Neurotensin
 * Neuromedin N (NTS1 selective)
 * PD-149,163 (NTS1 selective, reduced amide bond 8-13 fragment of neurotensin)


 * Non-peptide
 * Partial agonists derived from SR-48692

Antagonists

 * Levocabastine (NTS2 selective, also H1 histamine antagonist)
 * SR-48692 (NTS1 selective)
 * SR-142,948 (unselective, CAS# 184162-64-9)