RNF25

E3 ubiquitin-protein ligase RNF25 is an is_associated_with::enzyme that in humans is encoded by the RNF25 is_associated_with::gene.

Function
The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination.

Interactions
RNF25 has been shown to interact with is_associated_with::RELA.