IL13RA2

Interleukin-13 receptor subunit alpha-2 (IL-13Rα2), also known as CD213A2 (is_associated_with::cluster of differentiation 213A2), is a membrane bound is_associated_with::protein that in humans is encoded by the IL13RA2 is_associated_with::gene.

Function
IL-13Rα2 is closely related to IL-13Rα1, a subunit of the is_associated_with::interleukin-13 receptor complex. This protein binds IL13 with high affinity, but lacks any significant cytoplasmic domain, and does not appear to function as a signal mediator. It is, however able to regulate the effects of both IL-13 and IL-4, despite the fact it is unable to bind directly to the latter. It is also reported to play a role in the internalization of IL13.