PRSS3

Protease, serine, 3 is a is_associated_with::protein that in humans is encoded by the PRSS3 is_associated_with::gene.

Function
This gene encodes a is_associated_with::trypsinogen, which is a member of the is_associated_with::trypsin family of is_associated_with::serine proteases. This enzyme is expressed in the is_associated_with::brain and is_associated_with::pancreas and is resistant to common is_associated_with::trypsin inhibitors. It is active on is_associated_with::peptide linkages involving the carboxyl group of is_associated_with::lysine or is_associated_with::arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.