GDF10

Growth differentiation factor 10 (GDF10) also known as bone morphogenetic protein 3B (BMP-3B) is a is_associated_with::protein that in humans is encoded by the GDF10 is_associated_with::gene.

GDF10 belongs to the is_associated_with::transforming growth factor beta superfamily that is closely related to is_associated_with::bone morphogenetic protein-3 (BMP3). It plays a role in head formation and may have multiple roles in skeletal is_associated_with::morphogenesis. GDF10 is also known as BMP-3b, with GDF10 and BMP3 regarded as a separate subgroup within the TGF-beta superfamily.

In mice, GDF10 mRNA is abundant in the is_associated_with::brain, is_associated_with::inner ear, is_associated_with::uterus, is_associated_with::prostate, is_associated_with::neural tissues, is_associated_with::blood vessels and is_associated_with::adipose tissue with low expression in is_associated_with::spleen and is_associated_with::liver. It is also present in bone of both adults and is_associated_with::neonatal mice. Human GDF10 mRNA is found in the cochlea and lung of is_associated_with::foetuses, and in is_associated_with::testis, is_associated_with::retina, is_associated_with::pineal gland, and other neural tissues of adults.