Keratin 4

Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a is_associated_with::protein that in humans is encoded by the KRT4 is_associated_with::gene.

Keratin 4 is a is_associated_with::type II cytokeratins. It is specifically found in differentiated layers of the mucosal and esophageal epithelia together with is_associated_with::keratin 13. Mutations in the genes encoding this protein have been associated with is_associated_with::White Sponge Nevus, characterized by oral, esophageal, and anal is_associated_with::leukoplakia.