CEP250

Centrosome-associated protein CEP250 is a is_associated_with::protein that in humans is encoded by the CEP250 is_associated_with::gene. This gene encodes a core centrosomal protein required for is_associated_with::centriole-centriole cohesion during is_associated_with::interphase of the is_associated_with::cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of is_associated_with::mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. Furthermore, is_associated_with::CEP135 is also required for the centriolar localization of CEP250.