QKI

Quaking homolog, KH domain RNA binding (mouse), also known as QKI, is a is_associated_with::protein which in humans is encoded by the QKI is_associated_with::gene.

QKI belongs to a family of RNA-binding proteins called STAR proteins for Signal Transduction and Activation of RNA. They have an HNRNPK homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (is_associated_with::KHDRBS1) and SF1. Two more new members are is_associated_with::KHDRBS3 and is_associated_with::KHDRBS2.

The QKI gene is implicated as being important in schizophrenia, and QKI controls translation of many oligodendrocyte-related genes.