GABRD

Gamma-aminobutyric acid receptor subunit delta is a is_associated_with::protein that in humans is encoded by the GABRD is_associated_with::gene.

Function
is_associated_with::γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABAA receptors, which are ligand-gated chloride channels. The GABAA receptor is generally pentameric. Its five subunits are alpha, beta, gamma, delta, and rho. The GABRD gene encodes the delta subunit.

Cell type-specific expression
In a technical comparison between quantitative reverse transcriptase PCR and is_associated_with::digital PCR, the expression of the rat gabrd gene was examined across three cell types in the is_associated_with::somatosensory cortex: neurogliaform cells, fast spiking is_associated_with::basket cells and is_associated_with::pyramidal cells. Gene expression was detected in all three cell types, but showed marked enrichment in neurogliaform cells versus the other cell types examined.