HIST1H4L

Histone H4 is a is_associated_with::protein that in humans is encoded by the HIST1H4L is_associated_with::gene.

Function
is_associated_with::Histones are basic is_associated_with::nuclear proteins that are responsible for the is_associated_with::nucleosome structure of the is_associated_with::chromosomal fiber in is_associated_with::eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of is_associated_with::DNA is wrapped in repeating units, called is_associated_with::nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack is_associated_with::polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.