Rs71785313

The derived allele of indel rs71785313 (p.NYK388K) defines the APOL1 G2 allele. This allele has been shown to associate with kidney disease while conferring protection against Trypanosoma brucei rhodesiense.

Nearby variant rs12106505 is almost a complete proxy (r2>95%), so it can be used as an alternative for genotyping, especially in cases where the technology does not work well with indels.