PEX1

Peroxisome biogenesis factor 1, also known as PEX1, is a is_associated_with::protein which in humans is encoded by the PEX1 is_associated_with::gene.

This gene encodes a member of the AAA protein family, a large group of is_associated_with::ATPases associated with diverse cellular activities. This protein is is_associated_with::cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into is_associated_with::peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as is_associated_with::neonatal adrenoleukodystrophy, is_associated_with::infantile Refsum disease, and is_associated_with::Zellweger syndrome.

Interactions
PEX1 has been shown to interact with is_associated_with::PEX6 and is_associated_with::PEX26.