LZTR1

Leucine-zipper-like transcriptional regulator 1 is a is_associated_with::protein that in humans is encoded by the LZTR1 is_associated_with::gene.

This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic is_associated_with::leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the is_associated_with::Golgi complex.

Clinical significance
Deletion of this gene may be associated with is_associated_with::DiGeorge syndrome.

This gene has also been implicated in an autosomal dominant form of is_associated_with::schwannomatosis.