IBIDS syndrome

IBIDS syndrome, also known as trichothiodystrophy (TTD), photosynthetic trichthiodystrophy (TTDP), trichothiodystrophy with congenital ichthyosis, Tay syndrome or sulfur-deficient brittle hair syndrome,  was first described by Tay in 1971. It is an autosomal recessive congenital skin disease characterized by a congenital ichthyosiform erythroderma, growth and mental retardation, progeria-like facies, and brittle hair. The association of ichthyosis, brittle hair, intellectual impairment, decreased fertility, and short stature has been given the acronym IBIDS syndrome. In some cases, it can be diagnosed prenatally.

It is associated with ERCC2 and ERCC3.

Eponym
It is named after Dr. Tay Chong Hai, a Singaporean doctor who discovered and subsequently published a paper on it in 1971. Dr. Tay is the first doctor in South East Asia to be honored by having a disease named after him. Tay syndrome should not be confused with the Tay-Sachs disease.