SUPT5H

Transcription elongation factor SPT5 is a is_associated_with::protein that in humans is encoded by the SUPT5H is_associated_with::gene.

Interactions
SUPT5H has been shown to interact with is_associated_with::Cyclin-dependent kinase 7, is_associated_with::PIN1, is_associated_with::CDK9, is_associated_with::HTATSF1, is_associated_with::POLR2A, is_associated_with::PRMT1 and is_associated_with::Protein arginine methyltransferase 5.

Model organisms
is_associated_with::Model organisms have been used in the study of SUPT5H function. A conditional is_associated_with::knockout mouse line called Supt5tm2a(KOMP)Wtsi was generated at the is_associated_with::Wellcome Trust Sanger Institute. Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping

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