TMUB2

Transmembrane and ubiquitin-like domain-containing protein 2 is a is_associated_with::protein that in humans is encoded by the TMUB2 is_associated_with::gene.

Gene
TMUB2 maps on the human is_associated_with::chromosome 17, at locus 17q21.31. TMUB2 sits between two neighboring genes, ASB16-AS1 to the left and ATXN7L3 to the right. TMUB2 is 4.99Kb long. The TMUB2 is_associated_with::gene can be transcribed into three possible mRNA variants.

Expression
TMUB2 is likely ubiquitously expressed throughout the human body. It has a high expression level that is 2.9 times higher than other human is_associated_with::genes.

Protein
The TMUB2 is_associated_with::protein has a function that is not currently known. It consists of a 321 is_associated_with::amino acid long chain in humans. The human is_associated_with::protein has a molecular weight of 33.8kdal, an is_associated_with::isoelectric point of 4.73899, and three transmembrane regions. These will likely vary in orthologs.

Paralogs
TMUB1 is the only paralog of TMUB2. These is_associated_with::proteins share a 38% identity and 51% similarity.

Orthologs
The table below presents a selection of some of the TMUB2 orthologs to display is_associated_with::protein diversity among is_associated_with::species.

Protein Interactions
In humans, is_associated_with::Ubiquitin C (UBC) is a is_associated_with::protein with a known interaction with TMUB2. Other proposed interactions include is_associated_with::BCL2L13 (BCL2-like 13), is_associated_with::SGTA (Small glutamine-rich tetratricopeptide repeat-containing protein), and is_associated_with::UBQLN1 (Ubiquilin-1).