Transcription initiation protein SPT3 homolog

Transcription initiation protein SPT3 homolog is a is_associated_with::protein that in humans is encoded by the SUPT3H is_associated_with::gene.

Interactions
Transcription initiation protein SPT3 homolog has been shown to interact with is_associated_with::GCN5L2, is_associated_with::TAF6L, is_associated_with::TADA3L, is_associated_with::TAF5L, is_associated_with::SF3B3, is_associated_with::SUPT7L, is_associated_with::Myc, is_associated_with::TAF9, is_associated_with::Transformation/transcription domain-associated protein, is_associated_with::TAF12, is_associated_with::TAF10,  is_associated_with::TAF4 and is_associated_with::DDB1.

Model organisms
is_associated_with::Model organisms have been used in the study of SUPT3H function. A conditional is_associated_with::knockout mouse line called Supt3tm1a(EUCOMM)Hmgu was generated at the is_associated_with::Wellcome Trust Sanger Institute. Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping

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