MAST2

Microtubule-associated serine/threonine-protein kinase 2 is an is_associated_with::enzyme that in humans is encoded by the MAST2 is_associated_with::gene. The is_associated_with::protein encoded by this gene controls is_associated_with::TRAF6 and NF-kappaB activity.

Interactions
MAST2 has been shown to interact with is_associated_with::PCLKC.

Model organisms
is_associated_with::Model organisms have been used in the study of MAST2 function. A conditional is_associated_with::knockout mouse line called Mast2tm1a(KOMP)Wtsi was generated at the is_associated_with::Wellcome Trust Sanger Institute. Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping

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