Profilin 1

Profilin-1 is a is_associated_with::protein that in humans is encoded by the PFN1 is_associated_with::gene.

Function
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.

Interactions
Profilin 1 has been shown to interact with:
 * is_associated_with::FMNL1,
 * is_associated_with::MLLT4
 * is_associated_with::Vasodilator-stimulated phosphoprotein,
 * is_associated_with::WASF1, and
 * WASL.