ZFYVE27

Zinc finger, FYVE domain containing 27 is a is_associated_with::protein that in humans is encoded by the ZFYVE27 is_associated_with::gene.

Function
This gene encodes a protein with several is_associated_with::Transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote is_associated_with::Neuriteformation. A mutation in this gene has been reported to be associated with is_associated_with::Hereditary spastic paraplegia, however the is_associated_with::Pathogenicity of the mutation, which may simply represent a is_associated_with::Polymorphism (biology), is unclear. [provided by RefSeq, Mar 2010].