COUP-TFI

COUP-TF1 ( COUP T ranscription F actor 1 ) also known as NR2F1 ( N uclear R eceptor subfamily 2, group F , member 1 ) is a is_associated_with::protein that in humans is encoded by the NR2F1 is_associated_with::gene. This protein is a member of nuclear hormone receptor family of is_associated_with::steroid hormone receptors.

Function
Coup (chicken is_associated_with::ovalbumin upstream promoter) is_associated_with::transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates is_associated_with::initiation of transcription. COUP-TF1 binds to both direct repeats and is_associated_with::palindromes of the 5'-AGGTCA-3' motif.

Interactions
COUP-TFI has been shown to interact with:
 * is_associated_with::BCL11A,
 * is_associated_with::BCL11B,
 * is_associated_with::COPS2, and
 * ESR1.