ERP29

Endoplasmic reticulum protein 29 (ERp29) is a is_associated_with::chaperone protein that in humans is encoded by the ERP29 is_associated_with::gene.

Function
ERp29 is a reticuloplasmin, a protein which resides in the lumen of the is_associated_with::endoplasmic reticulum (ER). The protein shows sequence similarity to the is_associated_with::protein disulfide-isomerase family. However, it lacks the is_associated_with::thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of is_associated_with::secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.