SAP130

Histone deacetylase complex subunit SAP130 is an is_associated_with::enzyme that in humans is encoded by the SAP130 is_associated_with::gene.

Interactions
SAP130 has been shown to interact with is_associated_with::CSN1S1, is_associated_with::SIN3A, is_associated_with::Myc, is_associated_with::Von Hippel-Lindau tumor suppressor and is_associated_with::CUL2.

Model organisms
is_associated_with::Model organisms have been used in the study of SAP130 function. A conditional is_associated_with::knockout mouse line called Sap130tm1a(KOMP)Mbp was generated at the is_associated_with::Wellcome Trust Sanger Institute. Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping

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