Rs1805009

rs1805009, known as Asp294His or D294H and located in the MC1R gene, is the most common variant associated with red hair (redheads) and low tanning in one study. Reported as i3002507 by 23andMe in January 2015.

The risk allele is rs1805009(C), compared with the wild-type rs1805009(G) allele.

See also OMIM 155555.0001

blog about designing melanocortin analogs specific to these genotypes.