SLC14A2

Urea transporter, kidney also known as urea transporter 2 (UT2) or solute carrier family 14 member 2 (SLC14A2) is a is_associated_with::protein that in humans is encoded by the SLC14A2 is_associated_with::gene.

Function
In is_associated_with::mammalian cells, is_associated_with::urea is the chief end-product of is_associated_with::nitrogen is_associated_with::catabolism and plays an important role in the urinary concentration mechanism. Thus, the is_associated_with::plasma membrane of is_associated_with::erythrocytes and some renal epithelial cells exhibit an elevated urea permeability that is mediated by highly selective is_associated_with::urea transporters. In mammals, two urea transporters have been identified: the renal tubular urea transporter, UT2 (UT-A, and the erythrocyte urea transporter, UT11 (also called UT-B, coded for by the is_associated_with::SLC14A1 gene). SLC14A2 and is_associated_with::SLC14A1 constitute is_associated_with::solute carrier family 14.