RPS4Y1

40S ribosomal protein S4, Y isoform 1 is a is_associated_with::protein that in humans is encoded by the RPS4Y1 is_associated_with::gene.

Cytoplasmic is_associated_with::ribosomes, organelles that catalyze is_associated_with::protein synthesis, consist of a small is_associated_with::40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene, is_associated_with::RPS4Y2 and the ribosomal protein S4, X-linked (is_associated_with::RPS4X). The 3 isoforms encoded by these genes are not identical, but appear to be functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that is_associated_with::haploinsufficiency of the ribosomal protein S4 genes plays a role in is_associated_with::Turner syndrome; however, this hypothesis is controversial.