PABPC1

Polyadenylate-binding protein 1 is a is_associated_with::protein that in humans is encoded by the PABPC1 is_associated_with::gene.

Function
The poly(A)-binding protein (PAB or PABP), which is found complexed to the 3' poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM]

Interactions
PABPC1 has been shown to interact with:
 * is_associated_with::ANAPC5,
 * is_associated_with::CNOT7,
 * is_associated_with::EIF4G3,
 * EIF4G1,
 * is_associated_with::GSPT2,
 * is_associated_with::PAIP1,  and
 * is_associated_with::PAIP2.