HIST1H2BE

Histone H2B type 1-C/E/F/G/I is a is_associated_with::protein that in humans is encoded by the HIST1H2BE is_associated_with::gene.

Function
is_associated_with::Histones are basic nuclear proteins that are responsible for the is_associated_with::nucleosome structure of the chromosomal fiber in is_associated_with::eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of is_associated_with::DNA is wrapped in repeating units, called nucleosomes.

The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of is_associated_with::chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a is_associated_with::palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.