PDCD4

Programmed cell death protein 4 is a is_associated_with::protein that in humans is encoded by the PDCD4 is_associated_with::gene. It is one of the targets of an oncomiR, is_associated_with::MIRN21.

Function
This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified.

Interactions
PDCD4 has been shown to interact with is_associated_with::RPS13 and is_associated_with::Ribosomal protein L5.