Rs1554973

rs1554973 is a SNP near the toll-like receptor 4 TLR4 gene.

A study of 109 pregnant women focusing on TLR4 SNPs associated with chorionic plate inflammation concluded that rs1554973 was associated with increased risk when present in the fetal genome. The risk allele's increased odds ratio for clinically significant inflammation was 4.95 (CI: 3.0-5.6, p = .005).

No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis.

Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS).

Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.

Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.

Interaction between interleukin-1 receptor 2 and Toll-like receptor 4, and cervical cytokines.