PEX16

Peroxisomal membrane protein PEX16 is a is_associated_with::protein that in humans is encoded by the PEX16 is_associated_with::gene.

Function
The protein encoded by this gene is an integral peroxisomal membrane protein. An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes, suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene and two variants have been described.

Interactions
PEX16 has been shown to interact with is_associated_with::PEX19.