Endothelin 2

Endothelin 2, also known as ET-2, is a is_associated_with::protein that in humans is encoded by the EDN2 is_associated_with::gene.

Function
Endothelin 2 is a member of the is_associated_with::endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the is_associated_with::endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as is_associated_with::hypertension and is_associated_with::ovulation.