RPL10

60S ribosomal protein L10 is a is_associated_with::protein that in humans is encoded by the RPL10 is_associated_with::gene.

Function
is_associated_with::Ribosomes, the is_associated_with::organelles that catalyze protein synthesis, consist of a small is_associated_with::40S subunit and a large is_associated_with::60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L10E family of ribosomal proteins. It is located in the is_associated_with::cytoplasm. In vitro studies have shown that the chicken protein can bind to is_associated_with::c-Jun and can repress c-Jun-mediated transcriptional activation, but these activities have not been demonstrated in vivo. This gene was initially identified as a candidate for a is_associated_with::Wilms tumor suppressor gene, but later studies determined that this gene is not involved in the suppression of Wilms tumor. This gene has been referred to as 'is_associated_with::laminin receptor homolog' because a chimeric transcript consisting of sequence from this gene and sequence from the laminin receptor gene was isolated; however, it is not believed that this gene encodes a laminin receptor. Transcript variants utilizing alternative is_associated_with::polyA signals exist. The variant with the longest 3' UTR overlaps the is_associated_with::deoxyribonuclease I-like 1 gene on the opposite strand. This gene is co-transcribed with the small nucleolar RNA gene U70, which is located in its fifth is_associated_with::intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Interactions
RPL10 has been shown to interact with is_associated_with::YES1.