TNFRSF10B

Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, is a human is_associated_with::gene. Also known as: DR5, CD262, KILLER, TRICK2, TRICKB, ZTNFR9, TRAILR2, TRICK2A, TRICK2B, TRAIL-R2, KILLER/DR5

Interactions
TNFRSF10B has been shown to interact with is_associated_with::FADD, is_associated_with::TRAIL,   is_associated_with::Caspase 10 and is_associated_with::Caspase 8.

Cancer Therapy
Monoclonal antibodies targeting Death Receptor 5 (TNFRSF10B) have been developed and are currently under clinical trials for patients suffer from a variety of cancer types, see is_associated_with::Tigatuzumab (CS-1008).