Rs760761

g2b2mh blog In a population of healthy individuals, those that carry common variants (such as rs760761, rs1018381, rs2619522) located in the dysbindin (DTNBP1) gene, a risk factor for schizophrenia, show minor cognitive impairments such as decreased attentional capacity, worse performance on memory tasks, and alterations in schizotypal beliefs and experiences.

The association between several SNPs in the DTNBP1 gene, most especially rs760761, and schizophrenia was confirmed in a new sample of 1021 cases and 626 controls from Ireland.

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.

Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families.

The DTNBP1 (dysbindin) gene contributes to schizophrenia, depending on family history of the disease.

A powerful strategy to account for multiple testing in the context of haplotype analysis.

Association of the DTNBP1 locus with schizophrenia in a U.S. population.

Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia.

DTNBP1 genotype influences cognitive decline in schizophrenia.

Effect of 5-haplotype of dysbindin gene (DTNBP1) polymorphisms for the susceptibility to bipolar I disorder.

Dysbindin associated with selective serotonin reuptake inhibitor antidepressant efficacy.

Impact of schizophrenia candidate genes on schizotypy and cognitive endophenotypes at the population level.

Association between the DTNBP1 gene and intelligence: a case-control study in young patients with schizophrenia and related disorders and unaffected siblings.

Failure to confirm allelic and haplotypic association between markers at the chromosome 6p22.3 dystrobrevin-binding protein 1 (DTNBP1) locus and schizophrenia.

Is there protective haplotype of dysbindin gene (DTNBP1) 3 polymorphisms for major depressive disorder.

The dystrobrevin-binding protein 1 gene: features and networks.

Genetic associations with schizophrenia: meta-analyses of 12 candidate genes.

Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression.

Dysbindin gene (DTNBP1) in major depression: association with clinical response to selective serotonin reuptake inhibitors.

Association of the dystrobrevin binding protein 1 gene (DTNBP1) in a bipolar case-control study (BACCS).

A genome-wide investigation of SNPs and CNVs in schizophrenia.

The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variation.

Effect of the dysbindin gene on antimanic agents in patients with bipolar I disorder.

Dysbindin gene (DTNBP1) in major depressive disorder (MDD) patients: lack of association with clinical phenotypes.