Rs10090154

rs10090154 is a SNP in chromosome 8q24 "region 1", associated with increased risk for prostate cancer. The odds ratio for the (T) risk allele were 1.42 (CI: 1.07-1.87, p=0.014), and they were not significantly different between Caucasians and African-Americans in this study of ~500 patients.

In follow-up studies looking at disease severity (and not just overall risk), this SNP is reported to account for the risk (from region 1) of advanced prostate cancer.

Note that a meta-analysis across 10+ studies, including over 15,000 prostate cancer cases, reported the risk for a different SNP (rs1447295) representing the same region, "region 1", of this chromosome.


 * is_associated_with_disease::Prostate cancer
 * is_associated_with_disease::Colorectal cancer
 * is_associated_with_disease::Urinary bladder cancer