Cytoglobin

Cytoglobin is the protein product of CYGB, a is_associated_with::human and is_associated_with::mammalian is_associated_with::gene.

Cytoglobin is a is_associated_with::globin molecule ubiquitously expressed in all tissues and most notably utilized in is_associated_with::marine mammals. It was discovered in 2001 and named cytoglobin in 2002. It is thought to protect against hypoxia. The predicted function of cytoglobin is the transfer of oxygen from arterial blood to the brain.

Function
Cytoglobin is a ubiquitously expressed is_associated_with::hexacoordinate is_associated_with::hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge is_associated_with::nitric oxide or reactive oxygen species, or serve a protective function during is_associated_with::oxidative stress.

Applications
CYGB expression can be used as a specific marker with which is_associated_with::hepatic stellate cells can be distinguished from portal is_associated_with::myofibroblasts in the damaged human liver.