Rs12713559

rs12713559, also known as R3531C, is a SNP in the APOB apolipoprotein B gene.

The risk allele is A according to 23andMe, which tests for this SNP in regard to familial hypercholesterolemia type B, and where they note that the evidence is unclear about whether this mutation is causative on its own. In SNPedia, where we use the orientation as defined by dbSNP, the risk allele is rs12713559(T).

Familial Hypercholesterolemia Type B