Rs1495965

rs1495965 is one of several SNPs in the IL23R gene that has been shown in a large (over 1,000 Caucasian patients) study to be associated with ankylosing spondylitis. The odds ratio is 1.2 (p=6.6x10e-6).[PMID 17952073, PMID 18037607]

23andMe reports that the CC genotype at rs1495965 is associated with 1.56x higher odds of Beh&, and the TT genotype with 0.64x lower odds, than the CT genotype.

rs11209032 and rs1495965 no significant association with systemic sclerosis

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.

Investigation of the IL23R gene in a Spanish rheumatoid arthritis cohort.

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.

CARD15 and IL23R influences Crohn's disease susceptibility but not disease phenotype in a Brazilian population.

IL23R haplotypes provide a large population attributable risk for Crohn's disease.

IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease.

No association between interleukin 23 receptor gene polymorphisms and systemic lupus erythematosus.

Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.

An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.

Association study of IL10 and IL23R-IL12RB2 in Iranian patients with Behcet's disease.