CSPG4

Chondroitin sulfate proteoglycan 4, also known as melanoma-associated chondroitin sulfate proteoglycan (MCSP) or neuron-glial antigen 2 (NG2), is a is_associated_with::chondroitin sulfate proteoglycan that in humans is encoded by the CSPG4 is_associated_with::gene.

CSPG4 plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial is_associated_with::basement membranes. It represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.