RuvB-like 1

RuvB-like 1 (E. coli), also known as RUVBL1 and TIP49, is a human is_associated_with::gene. RUVBL1 can form a hexamer. The hexamer can form a dodecamer with is_associated_with::RUVBL2 protein. Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity.

Interactions
RuvB-like 1 has been shown to interact with:
 * is_associated_with::ACTL6A,
 * is_associated_with::Beta-catenin,
 * is_associated_with::EP400,
 * is_associated_with::Myc, and
 * is_associated_with::RUVBL2.