ADP-specific glucokinase

In is_associated_with::enzymology, an ADP-specific glucokinase also known as  ADP-dependent glucokinase is an is_associated_with::enzyme that catalyzes the is_associated_with::chemical reaction


 * ADP + D-glucose $$\rightleftharpoons$$ AMP + D-glucose 6-phosphate

Thus, the two substrates of this enzyme are ADP and is_associated_with::D-glucose, whereas its two products are AMP and is_associated_with::D-glucose 6-phosphate.

This enzyme belongs to the family of is_associated_with::transferases, to be specific those transferring phosphorus-containing groups (is_associated_with::phosphotransferases) with an alcohol group as acceptor.

In humans, the ADP-dependent glucokinase is encoded by the ADPGK is_associated_with::gene.

Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code.