Malignancy

Malignancy (from the Latin roots -male, "Bad" and -ignos, "Fire") is the tendency of a medical condition, especially tumors, to become progressively worse and to potentially result in death. Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis. Malignant is a corresponding adjectival medical term used to describe a severe and progressively worsening disease. The term is most familiar as a description of cancer. A malignant tumor may be contrasted with a non-cancerous benign tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues (metastasizing), while a benign tumor has none of those properties. Malignant tumor is synonymous with cancer. Uses of "malignant" in oncology:
 * Malignancy, malignant neoplasm, and malignant tumor are synonymous with cancer
 * Malignant ascites
 * Malignant transformation

Non-oncologic disorders referred to as "malignant":
 * Malignant hypertension
 * Malignant hyperthermia
 * ''Malignant otitis externa
 * Malignant tertian malaria (Malaria caused specifically by Plasmodium falciparum)
 * Neuroleptic malignant syndrome