GPX6

Glutathione peroxidase 6 (GPx-6) is an is_associated_with::enzyme that in humans is encoded by the GPX6 is_associated_with::gene.

This gene product belongs to the is_associated_with::glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Expression of this gene is restricted to embryos and adult olfactory epithelium.