YWHAB

14-3-3 protein beta/alpha is a is_associated_with::protein that in humans is encoded by the YWHAB is_associated_with::gene.

Function
This gene encodes a protein belonging to the is_associated_with::14-3-3 family of proteins, members of which mediate signal transduction by binding to is_associated_with::phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with is_associated_with::RAF1 and CDC25 is_associated_with::phosphatases, suggesting that it may play a role in linking is_associated_with::mitogenic signaling and the is_associated_with::cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.

Interactions
YWHAB has been shown to interact with:


 * BRAF,
 * is_associated_with::C-Raf,
 * is_associated_with::CD29,
 * is_associated_with::CDC25A,
 * is_associated_with::CDC25B,
 * is_associated_with::Cbl gene,
 * is_associated_with::EPB41L3,
 * is_associated_with::HDAC4
 * is_associated_with::KCNK3,
 * is_associated_with::MAPK7,
 * is_associated_with::PTPN3,
 * PRKCZ,
 * is_associated_with::RPS6KA1,
 * is_associated_with::TESK1,
 * is_associated_with::TNFAIP3, and
 * WEE1.