CCDC90B

Coiled coil domain containing 90B, also known as CCDC90B, is a protein encoded by the CCDC90B gene.

Gene
CCDC90B is located on is_associated_with::chromosome 11 in humans. It is neighbored by:
 * is_associated_with::PCF11, a mammalian pre-mRNA cleavage complex 2 protein
 * is_associated_with::ANKRD42, ankyrin repeat protein involved with calcium ion bonding
 * is_associated_with::BC070093
 * is_associated_with::DLG2, a member of the membrane-associated guanylate kinase (MAGUK) family

Structure
This protein is characterized by the presence of a domain of unknown function, DUF1640. This domain is a characteristic of the entire protein with the exception of the first twenty-three amino acid residues - MNSRQAWRLFLSQGRGDRWVSRP - which are a mitochondrial targeting site and cleaved.

The protein has seven predicted is_associated_with::alpha helices, a characteristic of coiled-coil proteins.

Predicted Properties
is_associated_with::Molecular Weight: 26.72 kDa

is_associated_with::Isoelectric point: 7.5

Transmembrane Helices: None

is_associated_with::Post-translation modifications:
 * Chloroplast transit peptides: None
 * Signal pepties: None
 * C-mannosylation sites: None
 * N-glycosylation sites: None
 * Mitochondrial targeting: Yes
 * Cleaved site: MNSRQAWRLFLSQGRGDRWVSRP

Cellular Location
CCDC90B is predicted to be a is_associated_with::mitochondrial protein with no transmembrane spans or segments. It is predicted to contain at least three specific phosphorylation sites: Protein Kinase C Phosphorylation sites, Casein Kinase II Phosphorylation sites, and cAMP/cGMP Dependant Phosphorylation sites.

Function
CCDC90B is not yet well understood by the scientific community.