MYF5

Myogenic factor 5 is a is_associated_with::protein that in humans is encoded by the MYF5 is_associated_with::gene. It is a is_associated_with::protein with a key role in regulating muscle differentiation or is_associated_with::myogenesis. Without Myf5 and MyoD, myogenic cells will fail to progress normally during the determination stage of is_associated_with::myogenesis due to underscoring of the dynamics between cell populations and MRF regulation.

Myf5 belongs to a family of proteins known as is_associated_with::myogenic regulatory factors (MRFs). These is_associated_with::bHLH (basic helix loop helix) is_associated_with::transcription factors act sequentially in myogenic differentiation. MRF family members include Myf5, is_associated_with::MyoD (Myf3), is_associated_with::myogenin, and is_associated_with::MRF4 (Myf6).