FKBP2

FK506-binding protein 2 is a is_associated_with::protein that in humans is encoded by the FKBP2 is_associated_with::gene.

Function
The is_associated_with::protein encoded by this gene is a member of the is_associated_with::immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a is_associated_with::cis-trans prolyl is_associated_with::isomerase that binds the immunosuppressants FK506 and is_associated_with::rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple is_associated_with::polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.

Interactions
FKBP2 has been shown to interact with is_associated_with::ARFGEF1 and is_associated_with::EPB41L2.