SC65

Synaptonemal complex protein SC65, also known as Leprecan-like protein 4 (LEPREL4) or nucleolar autoantigen No55, is a is_associated_with::protein that in humans is encoded by the LEPREL4 is_associated_with::gene.

Function
This nucleolar is_associated_with::protein was first characterized because it was an autoantigen in cases on is_associated_with::interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase is_associated_with::nucleolus, with a distribution distinct from that of nucleolar protein B23. During is_associated_with::mitosis it is associated with is_associated_with::chromosomes.