CDC23

Cell division cycle 23 homolog (S. cerevisiae), also known as CDC23, is a is_associated_with::protein that, in humans, is encoded by the CDC23 is_associated_with::gene.

Function
The CDC23 protein shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for is_associated_with::cell cycle progression through the G2/M transition. This protein is a component of is_associated_with::anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of is_associated_with::cyclin B-is_associated_with::ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Interactions
CDC23 has been shown to interact with is_associated_with::CDC27.