Angiopoietin-related protein 1

Angiopoietin-related protein 1 also known as angiopoietin-3 (ANG-3) is a is_associated_with::protein that in humans is encoded by the ANGPTL1 is_associated_with::gene.

Function
Angiopoietins are members of the is_associated_with::vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. is_associated_with::Angiopoietin-1, is_associated_with::angiopoietin-2, and is_associated_with::angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with is_associated_with::mRNA levels highest in highly vascularized tissues. This protein was found to be a is_associated_with::secretory protein that does not act as an is_associated_with::endothelial cell is_associated_with::mitogen in vitro.