SOCS7

Suppressor of cytokine signaling 7 is a is_associated_with::protein that in humans is encoded by the SOCS7 is_associated_with::gene.

Model organisms
is_associated_with::Model organisms have been used in the study of SOCS7 function. A conditional is_associated_with::knockout mouse line, called Socs7tm1a(EUCOMM)Wtsi was generated as part of the is_associated_with::International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.

Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Twenty five tests were carried out on is_associated_with::mutant mice and one significant abnormality was observed: homozygous mutant males showed a decreased response to stress-induced is_associated_with::hyperthermia.

Interactions
SOCS7 has been shown to interact with is_associated_with::NCK1.