ZWINT

ZW10 interactor (Zwint-1) is a is_associated_with::protein that in humans is encoded by the ZWINT is_associated_with::gene.

Function
Zwint-1 is clearly involved in is_associated_with::kinetochore function although an exact role is not known. It interacts with is_associated_with::ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late is_associated_with::anaphase. It has a uniform distribution in the is_associated_with::cytoplasm of is_associated_with::interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Interactions
ZWINT has been shown to interact with is_associated_with::MIS12.