Rs3738919

rs3738919, a SNP located in the ITGAV gene, was identified in a European study to be associated with rheumatoid arthritis (RA).

The risk allele for rs3738919 is the more common allele, (C). For the three European Caucasian populations studied (372 RA patients + 330 controls), and combining the (C;C) and (A;C) genotypes in comparison to the (A;A) genotype, the odds ratio for RA = 1.94 (CI: 1.3â€“2.9, p = 0.002). There was no significant difference in RA risk between those carrying one or two (C) alleles.

An editorial about this finding has been published.


 * is_associated_with_disease::Rheumatoid arthritis