NOX5

NADPH oxidase, EF-hand calcium binding domain 5, also known as NOX5, is a is_associated_with::protein which in humans is encoded by the NOX5 is_associated_with::gene.

Function
NOX5 is a novel is_associated_with::NADPH oxidase that generates is_associated_with::superoxide.

Nox5 interacts with c-abl, superoxide production leads to is_associated_with::phosphorylation of c-abl, while inhibition of c-abl kinase activity inhibits Nox5 superoxide production.