PAWR

PRKC, apoptosis, WT1, regulator, also known as PAWR or Prostate apoptosis response-4 (Par-4), is a human is_associated_with::gene coding for a tumor-suppressor is_associated_with::protein that induces is_associated_with::apoptosis in is_associated_with::cancer cells, but not in normal cells.

The active domain of the Par-4 protein has been found to confer cancer resistance in is_associated_with::transgenic mice without compromising normal viability or aging, and may have is_associated_with::therapeutic significance.

Interactions
PAWR has been shown to interact with is_associated_with::WT1, is_associated_with::THAP1, is_associated_with::SLC5A1, is_associated_with::DAPK3, is_associated_with::Apoptosis antagonizing transcription factor and is_associated_with::Protein kinase Mζ.