Bromodomain and WD repeat-containing protein 1

Bromodomain and WD repeat-containing protein 1 (BRWD1) also known as WD repeat-containing protein 9 (WDR9) is a is_associated_with::protein that in humans is encoded by the BRWD1 is_associated_with::gene.

Function
This gene encodes a member of the is_associated_with::WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 is_associated_with::amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or is_associated_with::multiprotein complexes. Members of this family are involved in a variety of cellular processes, including is_associated_with::cell cycle progression, is_associated_with::signal transduction, is_associated_with::apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats, and the function of this protein is not known. This gene is located within the is_associated_with::Down syndrome region-2 on is_associated_with::chromosome 21. Alternative splicing of this gene generates 3 transcript variants diverging at the 3' ends.