Rs3817198

rs3817198 is a SNP in the LSP1 gene on chromosome 11. The less frequent allele rs3817198(C) increases risk of breast cancer by about +10% in Caucasians, but actually may be protective in women of African ancestry.

rs3817198, a SNP associated with the LSP1 gene, was one of the four strongest associating SNPs found in a genome-wide association study of over 4,000 breast cancer samples.