COUP-TFII

COUP-TFII (COUP transcription factor 2), also known as NR2F2 (nuclear receptor subfamily 2, group F, member 2) is a is_associated_with::protein that in humans is encoded by the NR2F2 is_associated_with::gene. The COUP acronym stands for chicken ovalbumin upstream promoter.

Function
COUP-TFII plays a critical role in controlling the development of a number of tissues and organs including heart, blood vessels, muscles and limbs.

The is_associated_with::glucocorticoid receptor (GR) stimulates COUP-TFII-induced is_associated_with::transactivation while COUP-TFII represses the GR transcriptional activity. COUP-TFII interacts with is_associated_with::GATA2 to inhibit is_associated_with::adipocyte differentiation.

Interactions
COUP-TFII has been shown to interact with:
 * is_associated_with::HDAC1
 * is_associated_with::Lck
 * is_associated_with::V-erbA-related gene.
 * is_associated_with::Nucleolin