Rs3740753

Part of a haplotype Gs286, standalone effect for endometrial cancer is ambiguous. Tightly linked with PROGINS allele.

Some evidence of interaction on caucasian/hispanic patients with 17-alpha-hydroxyprogesterone caproate for reducing recurrent preterm birth detected.

PROGINS allele and this SNP in particular were found to not be involved in male infertility.

Association of progesterone receptor gene polymorphism with male infertility and clinical outcome of ICSI

Progesterone receptor polymorphisms and clinical response to 17-alpha-hydroxyprogesterone caproate

Clarifying the PROGINS allele association in ovarian and breast cancer risk: a haplotype-based analysis