CD80

Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated is_associated_with::B cells and is_associated_with::monocytes that provides a costimulatory signal necessary for is_associated_with::T cell activation and survival. It is the ligand for two different proteins on the T cell surface: is_associated_with::CD28 (for autoregulation and intercellular association) and is_associated_with::CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with is_associated_with::CD86 to prime T cells.