SNAPC4

snRNA-activating protein complex subunit 4 is a is_associated_with::protein that in humans is encoded by the SNAPC4 is_associated_with::gene.

Model organisms
is_associated_with::Model organisms have been used in the study of SNAPC4 function. A conditional is_associated_with::knockout mouse line, called Snapc4tm1a(KOMP)Wtsi was generated as part of the is_associated_with::International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists — at the is_associated_with::Wellcome Trust Sanger Institute.

Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Twenty six tests were carried out on is_associated_with::mutant mice and two significant abnormalities were observed. No is_associated_with::homozygous mutant embryos were recorded during gestation and, in a separate study, no homozygous animals were observed at is_associated_with::weaning. The remaining tests were carried out on adult is_associated_with::heterozygous mutant animals and no further abnormalities were observed.

Interactions
SNAPC4 has been shown to interact with is_associated_with::SNAPC1, is_associated_with::POU2F1 and is_associated_with::SNAPC2.