DOK2

Docking protein 2 is a is_associated_with::protein that in humans is encoded by the DOK2 is_associated_with::gene.

Function
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

Interactions
DOK2 has been shown to interact with is_associated_with::INPP5D and is_associated_with::TEK tyrosine kinase.