SEPT2

Septin 2, also known as SEPT2, is a is_associated_with::protein which in humans is encoded by the SEPT2 is_associated_with::gene.

Function
SEPT2 can hetero-oligomerize with is_associated_with::SEPT6 and is_associated_with::SEPT7 to form filaments. SEPT2 interacted with SEPT6 through its C-terminal is_associated_with::coiled-coil domain. Knockdown of SEPT2, SEPT6, and SEPT7 in causes is_associated_with::actin stress fibers to disintegrate and cells to lose polarity. Septins, is_associated_with::SOCS7, and is_associated_with::NCK1 are part of a signaling pathway that couples regulation of the DNA damage response to the cytoskeleton.

Interactions
SEPT2 has been shown to interact with:
 * is_associated_with::SEPT6
 * is_associated_with::SEPT7, and
 * is_associated_with::SEPT9.