SSX5

Protein SSX5 is a is_associated_with::protein that in humans is encoded by the SSX5 is_associated_with::gene.

Function
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and is_associated_with::cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. is_associated_with::SSX1, is_associated_with::SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all is_associated_with::synovial sarcomas. This gene appears not to be involved in this type of is_associated_with::chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.