Rs2580520

Genetic variants at 1p11.2 and breast cancer risk: a two-stage study in Chinese women.

one SNP (rs2580520) located at a predicted enhancer region of SRGAP2 was consistently associated with a significantly increased risk of breast cancer in a recessive genetic model [Odds Ratio (OR) &#8202;=&#8202; 1.66, 95% confidence interval (CI) &#8202;=&#8202; 1.16-2.36 for stage 2 samples; OR &#8202;=&#8202; 1.51, 95% CI &#8202;=&#8202; 1.16-1.97 for combined samples, respectively].