PDSS2

Decaprenyl-diphosphate synthase subunit 2 (PDSS2), also known as candidate tumor suppressor protein, is a is_associated_with::protein that in humans is encoded by the PDSS2 is_associated_with::gene.

Function
The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis.

Clinical significance
It may be associated with is_associated_with::Coenzyme Q10 deficiency.