HCN2

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 is a is_associated_with::protein that in humans is encoded by the HCN2 is_associated_with::gene.

Interactions
HCN2 has been shown to interact with is_associated_with::HCN1 and is_associated_with::HCN4.

Function
The function of the channel is not known although its activation by hyperpolarization alludes to the is_associated_with::funny channels in the is_associated_with::sinoatrial node of the heart (which form the basis of spontaneous generation of electrical rhythm). These channels have recently been associated with chronic pain and blocking the gene is associated with resolution of neuropathic episodes of is_associated_with::pain.