Rs111033258

rs111033258, also known as N48K or Asn48Lys, is a SNP in the clarin 1 CLRN1 gene on chromosome 3.

Most common in Ashkenazi Jews, the risk allele rs111033258(G) leads to Usher Syndrome Type III if inherited in two copies. Note that in 23andMe, the orientation is reversed from dbSNP, so the risk allele for the equivalent SNP, i4990151, is (C).