Rs3746544

SNPs nominally associated with schizophrenia (rs3787283, rs3746544) were the same as those previously demonstrated to be associated with ADHD but with the opposite alleles, allowing the intriguing hypothesis that genetic variation at SNAP25 may be differentially associated with both schizophrenia and ADHD

When comparing pooled results of multiple ADHD studies, only rs3746544(A) was found to have a significant association (p=0.028) with slightly increased risk (OR 1.15 at 95%) of ADHD.

Support for the MnlI polymorphism of SNAP25; a Korean ADHD case-control study.

Investigation of variation in SNAP-25 and ADHD and relationship to co-morbid major depressive disorder.

Biased paternal transmission of SNAP-25 risk alleles in attention-deficit hyperactivity disorder.