H3F3B (gene)

H3 histone, family 3B (H3.3B) is a is_associated_with::protein in humans that is encoded by the H3F3B is_associated_with::gene.

is_associated_with::Histones are basic nuclear proteins that are responsible for the is_associated_with::nucleosome structure of the chromosomal fiber in is_associated_with::eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of is_associated_with::chromatin into higher order structures. This gene contains is_associated_with::introns and its mRNA is poyadenylated, unlike most histone genes. The protein encoded is a member of the histone H3 family. [provided by RefSeq, Jul 2008]. Unlike most histone genes, H3F3B is not located in a cluster, but rather is isolated in the telomeric region of Chromosome 17.