PCNT

Pericentrin (kendrin), also known as PCNT, is a is_associated_with::protein which in humans is encoded by the PCNT is_associated_with::gene.

Function
The protein encoded by this gene binds to is_associated_with::calmodulin and is expressed in the is_associated_with::centrosome. It is an integral component of the is_associated_with::pericentriolar material (PCM). The protein contains a series of is_associated_with::coiled coil domains and a highly conserved PCM targeting motif called the PACT domain near its is_associated_with::C-terminus. The protein interacts with the is_associated_with::microtubule nucleation component γ-tubulin and is likely important to normal functioning of the centrosomes, is_associated_with::cytoskeleton, and is_associated_with::cell cycle progression.

Interactions
PCNT has been shown to interact with is_associated_with::PCM1.