Thymosin beta-4

Thymosin beta-4 is a is_associated_with::protein that in humans is encoded by the TMSB4X is_associated_with::gene.

The protein consists (in humans) of 43 is_associated_with::amino acids (msdkpdmaei ekfdksklkk tetqeknplp sketieqekq ages) molWt 4921.

Function
This gene encodes an is_associated_with::actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes is_associated_with::X inactivation and has a homolog on chromosome Y (TMSB4Y).

Clinical significance
It has been studied in a number of clinical trials.

The thymosin beta-4 peptide, if used after a heart attack, might reactivate cardiac is_associated_with::progenitor cells to repair damaged heart tissue.

Doping in Sports
Thymosin beta-4 was allegedly used by some players in various Australian football codes and is under investigation by the Australian Sports Anti-Doping Authority for anti-doping violations

Players of the Essendon Football Club were cleared of use of Thymosin Beta 4 on March 30th, 2015

Interactions
TMSB4X has been shown to interact with ACTA1 and is_associated_with::ACTG1.