IFT140

IFT140, Intraflagellar transport 140 homolog, is a is_associated_with::protein that in humans is encoded by the IFT140 is_associated_with::gene.

Clinical significance
Mutations in this gene have been associated to cases of skeletal is_associated_with::ciliopathy.

Model organisms
is_associated_with::Model organisms have been used in the study of IFT140 function. A conditional is_associated_with::knockout mouse line called Ift140tm1a(KOMP)Wtsi was generated at the is_associated_with::Wellcome Trust Sanger Institute. Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping

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