Rs1012729

rs1012729 is a SNP in the WNK lysine deficient protein kinase 1 WNK1 gene.

In the Avon Longitudinal Study of Parent and Children Study (5326 subjects measured for systolic blood pressure at 11 years of age), rs1012729(G) carriers were associated with a gender-adjusted change in a diastolic blood pressure gradient of -0.11 mm Hg/y (CI: -0.20 to -0.03 mm Hg/y; p=0.0054). This variant also showed association with systolic blood pressure.