SEPT7

Septin-7 is a is_associated_with::protein that in humans is encoded by the SEPT7 is_associated_with::gene.

Function
This gene encodes a protein that is highly similar to the is_associated_with::CDC10 protein of is_associated_with::Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of is_associated_with::Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for is_associated_with::cytokinesis. Although the exact function of this gene has not yet been determined, its high similarity to yeast CDC10 and the high conservative nature of eukaryotic cell cycle machinery suggest a similar role to that of its yeast counterpart. Alternative splicing results in two transcript variants encoding different isoforms.

Interactions
SEPT7 has been shown to interact with is_associated_with::SEPT2 and is_associated_with::SEPT9.