CEP63

Centrosomal protein of 63 kDa is a is_associated_with::protein that in humans is encoded by the CEP63 is_associated_with::gene. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Function
This gene encodes a protein with six is_associated_with::coiled-coil domains. The protein is localized to the is_associated_with::centrosome, a non-membraneous is_associated_with::organelle that functions as the major is_associated_with::microtubule-organizing center in animal cells. Recent computational analysis revealed pathogenic property of L61P point mutation in CEP63 protein that affected its native structural conformation.

Interactions
CEP63 has been shown to interact with is_associated_with::DISC1, is_associated_with::CEP152 and is_associated_with::CDK1.