Rs3025039

rs3025039, also known as the +936C/T SNP in the VEGFA gene, has been associated with age-related macular degeneration (ARMD).

A study of 190 Taiwanese patients with late wet age related macular degeneration found that the rs3025039(T) allele was associated with increased risk, with an odds ratio of 2.61 (CI: 1.68 to 4.07, p = 1.45 x 10e-5).

Note that this association may be completely due to the tight linkage (D' = 0.99) between this SNP and rs1061170, which has been reported by numerous studies to be associated with ARMD.

C->T was associated with increased risk for altitude sickness.

Vascular endothelial growth factor gene polymorphisms in Behcet's disease.

Polymorphisms in the vascular endothelial growth factor gene and breast cancer in the Cancer Prevention Study II cohort.

Vascular endothelial growth factor gene haplotypes in Kawasaki disease.

VEGF, FGF1, FGF2 and EGF gene polymorphisms and psoriatic arthritis.

Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk.

A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.

Vascular endothelial growth factor (VEGF) gene (VEGFA) polymorphism can predict the prognosis in acute myeloid leukaemia patients.

VEGF polymorphisms and survival in early-stage non-small-cell lung cancer.

Polymorphisms in the vascular endothelial growth factor gene and the risk of familial endometriosis.

Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.

Genetic polymorphisms of VEGF, interactions with cigarette smoking exposure and esophageal adenocarcinoma risk.

Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.

Vascular endothelial growth factor gene polymorphisms may predict the risk of acute graft-versus-host disease following allogeneic transplantation: preventive effect of vascular endothelial growth factor gene on acute graft-versus-host disease.

Variation in the vascular endothelial growth factor gene, carotid intima-media thickness and the risk of acute myocardial infarction.

Combinational polymorphisms of seven CXCL12-related genes are protective against breast cancer in Taiwan.

EGFR pathway polymorphisms and bladder cancer susceptibility and prognosis.

Polymorphisms in genes involved in DNA repair, cell growth, oxidative stress and inflammatory response, and melanoma risk.

Effect of polymorphisms in the 3' untranslated region (3'-UTR) of vascular endothelial growth factor gene on gastric cancer and peptic ulcer diseases in Japan.

Polymorphisms of TGFB1 and VEGF genes and survival of patients with gastric cancer.

Vascular endothelial growth factor polymorphisms and esophageal cancer prognosis.

An analysis of growth, differentiation and apoptosis genes with risk of renal cancer.

Polymorphism of the manganese superoxide dismutase gene but not of vascular endothelial growth factor gene is a risk factor for diabetic retinopathy.

The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors.

Association of vascular endothelial growth factor polymorphisms with asthma in Tunisian children.

The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer.

Polymorphisms in the VEGFA and VEGFR-2 genes and neovascular age-related macular degeneration.

Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism.

The association of 18F-deoxyglucose (FDG) uptake of PET with polymorphisms in the glucose transporter gene (SLC2A1) and hypoxia-related genes (HIF1A, VEGFA, APEX1) in non-small cell lung cancer. SLC2A1 polymorphisms and FDG-PET in NSCLC patients.

Gene polymorphism of vascular endothelial growth factor -1154 G>A is associated with hypertensive nephropathy in a Hispanic population.

Vascular endothelial growth factor gene polymorphisms and rheumatoid arthritis.

Genetics of VEGF serum variation in human isolated populations of cilento: importance of VEGF polymorphisms.

Interaction between smoking and polymorphism in the promoter region of the VEGFA gene is associated with ischemic heart disease and myocardial infarction in rheumatoid arthritis.

Contribution of VEGF polymorphisms to variation in VEGF serum levels in a healthy population.

Vascular endothelial growth factor (VEGF) gene polymorphisms may influence the efficacy of thalidomide in multiple myeloma.

Polymorphisms of the vascular endothelial growth factor gene and severe radiation pneumonitis in non-small cell lung cancer patients treated with definitive radiotherapy.

Polymorphism in the vascular endothelial growth factor A (VEGFA) gene is associated with serum VEGF-A level and disease activity in rheumatoid arthritis: differential effect of cigarette smoking.

Role of Vascular Endothelial Growth Factor Polymorphisms in the Treatment Success in Patients with Wet Age-related Macular Degeneration.