Rs63749851

rs63749851, also known as T122P or Thr122Pro, is a SNP in the presenilin 2 PSEN2 gene.

Inherited as an autosomal dominant, the rare rs63749851(C) allele is considered causative for early-onset Alzheimer's disease, as reported in. If you are aware of individuals carrying this allele who are past the age of 50 and who are not Alzheimer patients, please let us know.