Brunner syndrome

Brunner syndrome is a rare genetic disorder caused by a mutation in the MAOA gene. It is characterized by mild mental retardation and problematic impulsive behavior (such as arson, hypersexuality, and aggressive posturing). It is caused by a monoamine oxidase A (MAOA) deficiency, which leads to an excess of monoamines in the brain, such as serotonin, dopamine, and epinephrine.

It was characterized in 1993.