Rs10086908

rs10086908 is a SNP in the 8q24 chromosomal region, which has been linked in several studies to prostate cancer.

In a study of 1,563 patients of European ancestry, rs10086908 was designated as the representative of a prostate cancer risk region termed "locus 3", with an odds ratio of 1.70 (CI: 1.39-2.07) for carriers of a risk genotype. Two other regions of chromosome 8q24 were also studied.

Confirmation study of prostate cancer risk variants at 8q24 in African Americans identifies a novel risk locus.

Homozygous deletions and recurrent amplifications implicate new genes involved in prostate cancer.


 * is_associated_with_disease::Prostate cancer