SASS6

Spindle assembly abnormal protein 6 homolog (SAS-6) is a is_associated_with::protein that in humans is encoded by the SASS6 is_associated_with::gene.

Function
SAS-6 is necessary for is_associated_with::centrosome duplication and functions during procentriole formation; SAS-6 functions to ensure that each is_associated_with::centriole seeds the formation of a single procentriole per is_associated_with::cell cycle.

Clinical significance
Mutations in SASS6 are associated to MCPH.