Sp8 transcription factor

Transcription factor Sp8 also known as specificity protein 8 (SP-8) or Btd transcription factor (buttonhead) is a is_associated_with::protein that in humans is encoded by the SP8 is_associated_with::gene. Sp8 is a is_associated_with::transcription factor in the is_associated_with::Sp/KLF family.

Function
Sp8 mediates limb outgrowth during early development. Sp8 deletion in mice resulted in severe is_associated_with::exencephaly.