POLR2C

DNA-directed RNA polymerase II subunit RPB3 is an is_associated_with::enzyme that in humans is encoded by the POLR2C is_associated_with::gene.

Function
This gene encodes the third largest subunit of is_associated_with::RNA polymerase II, the polymerase responsible for synthesizing messenger is_associated_with::RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, is_associated_with::POLR2J. These two subunits form a core subassembly unit of the polymerase. A is_associated_with::pseudogene has been identified on chromosome 21.

Interactions
POLR2C has been shown to interact with:


 * is_associated_with::ATF4,
 * is_associated_with::CCHCR1,
 * is_associated_with::Myogenin,
 * is_associated_with::POLR2A,
 * is_associated_with::POLR2B,
 * is_associated_with::POLR2E and
 * is_associated_with::POLR2F,
 * is_associated_with::POLR2G,
 * is_associated_with::POLR2H,
 * is_associated_with::POLR2J,
 * is_associated_with::POLR2K,
 * is_associated_with::POLR2L, and
 * is_associated_with::TAF15.