MED31

Mediator of RNA polymerase II transcription subunit 31 is a protein in humans encoded by the MED31 is_associated_with::gene. It represents subunit Med31 of the Mediator complex. The family contains the Saccharomyces cerevisiae SOH1 homologues. SOH1 is responsible for the repression of is_associated_with::temperature sensitive growth of the HPR1 is_associated_with::mutant and has been found to be a component of the RNA polymerase II transcription complex. SOH1 not only interacts with factors involved in DNA repair, but transcription as well. Thus, the SOH1 protein may serve to couple these two processes.