PLCB4

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 is an is_associated_with::enzyme that in humans is encoded by the PLCB4 is_associated_with::gene.

Function
The protein encoded by this gene is_associated_with::catalyzes the formation of is_associated_with::inositol 1,4,5-trisphosphate and is_associated_with::diacylglycerol from is_associated_with::phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the is_associated_with::intracellular transduction of many is_associated_with::extracellular signals in the retina. Two transcript variants encoding different is_associated_with::isoforms have been found for this gene.