Cathepsin L2

Cathepsin L2, also known as cathepsin V and encoded by the CTSL2 gene, is a human is_associated_with::gene.

The protein encoded by this gene, a member of the is_associated_with::peptidase is_associated_with::C1 family, is a lysosomal cysteine proteinase that may play an important role in is_associated_with::corneal physiology. This gene is expressed in colorectal and is_associated_with::breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in is_associated_with::tumor processes.

Clinical significance
Cathepsin L2 may play a role in the pathogenesis of is_associated_with::keratoconus.