PRSS8

Prostasin is a is_associated_with::protein that in humans is encoded by the PRSS8 is_associated_with::gene.

This gene encodes a is_associated_with::trypsinogen, which is a member of the trypsin family of is_associated_with::serine proteases. This is_associated_with::enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of is_associated_with::lysine or is_associated_with::arginine.

The protein is implicated in epithelial is_associated_with::sodium channel regulation and may help regulate a variety of tissue functions that involve a sodium channel.