ATP5J

ATP synthase-coupling factor 6, mitochondrial is an is_associated_with::enzyme that in humans is encoded by the ATP5J is_associated_with::gene.

The F6 subunit is part of the peripheral stalk that links the F1 and FO complexes together, and which acts as a stator to prevent certain subunits from rotating with the central rotary element. The peripheral stalk differs in subunit composition between is_associated_with::mitochondrial, is_associated_with::chloroplast and is_associated_with::bacterial is_associated_with::F-ATPases. In mitochondria, the peripheral stalk is composed of one copy each of subunits OSCP (oligomycin sensitivity conferral protein), F6, B and D. There is no homologue of subunit F6 in bacterial or chloroplast F-ATPase, whose peripheral stalks are composed of one copy of the delta subunit (homologous to OSCP), and two copies of subunit B in bacteria, or one copy each of subunits B and B' in chloroplasts and is_associated_with::photosynthetic bacteria.