Rs7997012

rs7997012, located in an intron of the HTR2A gene, was found to be associated with a somewhat increased rate of successful response to treatment of depression with the drug citalopram.

From this article :

"HTR2A encodes the serotonin 2A receptor, which is downregulated by citalopram. Participants who were homozygous for the A allele had an 18% reduction in absolute risk of having no response to treatment, compared with those homozygous for the other allele."


 * See also Anxiety Blog posting


 * is_associated_with_disease::Major depressive disorder
 * is_associated_with_disease::Generalized anxiety disorder
 * is_associated_with_disease::Bipolar disorder