TLR

The three letter abbreviation TLR can mean
 * Teaching and learning responsibility - in Great Britain, special payments awarded teachers who have taken on "significant responsibility that is not required of all classroom teachers"
 * Tony La Russa St. Louis Cardinals manager
 * Twin-lens reflex camera, a photo camera with two lenses

Biology

 * Target Lesion Revascularization, concept in cardiac studies in which the different forms of coronary intervention (coated, uncoated stents) are compared.
 * Toll-like receptors, proteins constituting an important part of the immune system
 * Tonic labyrinthine reflex, a primitive reflex found in newborn humans
 * Tubal Ligation Reversal or Tubal reversal, surgery to open and reconnect the fallopian tube after a tubal ligation procedure
 * Two Legged Rat - A person undergoing experimental medical treatment

Communications

 * Tasteful Licks Records, an Independent Record Label
 * The local radio station (Thanet Local Radio), now known as KMFM Thanet

Reviews

 * Suffolk Transnational Law Review
 * Texas Law Review
 * The Literary Review, an American literary magazine published by Fairleigh Dickinson University
 * Tulane Law Review

Travel

 * TL1000R, a motorcycle with a 998cc v-twin engine manufactured by Suzuki
 * The IATA airport code for Mefford Field, California, USA
 * Air Libya, Libya (ICAO airline code)

Fiction

 * BIONICLE: The Legend Reborn, a 2009 film based on the Lego Bionicle franchise
 * To Love-Ru
 * The Last Remnant, a turn-based RPG game made by Square Enix

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