Rs2070106

Based on a study of 790 individuals from 245 nuclear families (220 families were European Caucasian; 300 of the probands had a diagosis of schizophrenia), the rs2070106(G) allele was overtransmitted to affected offspring.

This actually conflicts with a previous report in which the rs2070106(A) allele was identified (also in Caucasians) in a combined gene association/expression study as associated with schizophrenia.

This is either a case of the "flip-flop" phenomenon in which multilocus effects and variation in interlocus correlations reverse a previously reported association, or perhaps more likely, a false positive.


 * is_associated_with_disease::Schizophrenia
 * is_associated_with_disease::Syndrome