Rs3732378

rs3732378 VAL249ILE is tightly linked to neighboring rs3732379 THR280MET

The protein receptor with both variant amino acids is known as CX3CR1-M280.

the minor alleles of this pair are associated with
 * more rapid progression to full-blown AIDS and probably increased susceptibility to HIV infection
 * reduced risk of acute coronary events
 * increased risk of age related macular degeneration