GUCY1A3

Guanylate cyclase soluble subunit alpha-3 is an is_associated_with::enzyme that in humans is encoded by the GUCY1A3 is_associated_with::gene.

Function
is_associated_with::Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for is_associated_with::nitric oxide and is_associated_with::nitrovasodilator drugs. Mutations in this gene have been associated to cases of is_associated_with::myocardial infarction (10.1038/nature12722).