XRCC3

DNA repair protein XRCC3 is a is_associated_with::protein that in humans is encoded by the XRCC3 is_associated_with::gene.

Function
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Interactions
XRCC3 has been shown to interact with is_associated_with::RAD51C.