Rs7775228

rs7775228 is one of three HLA region SNPs used to tag the DQ2.2 haplotype in gs221.

rs7775228(T) was found to be associated with increased risk for osteoarthritis among Japanese, but not Europeans, with an odds ratio of 1.34 (CI: 1.21-1.49, combined p = 2.43×10e?8). This SNP is also in linkage disequilibrium with rs10947262, which was found to be associated in multiple populations with osteoarthritis.


 * is_associated_with_disease::Rheumatoid arthritis
 * is_associated_with_disease::Osteoarthritis