S100A4

S100 calcium-binding protein A4 (S100A4) is a is_associated_with::protein that in humans is encoded by the S100A4 is_associated_with::gene.

Function
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Interactions
S100A4 has been shown to interact with is_associated_with::S100 calcium binding protein A1.