Rs80357093

rs80357093 is a SNP causing an amino acid change in the breast cancer 1 BRCA1 gene at amino position 61. The more common rs80357093(G) allele (in dbSNP orientation) encodes Cys, while the rare rs80357093(A) allele encodes Tyr; this variation is also known as Cys61Tyr or C61Y.

This variant is considered pathogenic for breast cancer by ClinVar's Sharing Clinical Reports Project.