CD11c

CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a is_associated_with::gene that encodes for CD11c.

CD11c is a type I is_associated_with::transmembrane protein found at high levels on most is_associated_with::human is_associated_with::dendritic cells, but also on is_associated_with::monocytes, is_associated_with::macrophages, is_associated_with::neutrophils, and some is_associated_with::B cells that induces cellular activation and helps trigger is_associated_with::neutrophil respiratory burst; expressed in is_associated_with::hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.