RAB18

Ras-related protein Rab-18 is a is_associated_with::protein that in humans is encoded by the RAB18 is_associated_with::gene.

Rab18 is a ubiquitously expressed protein with particularly high expression in the is_associated_with::brain. Rab18 was first characterised as an is_associated_with::endosomal protein in epithelial cells of mouse kidney and intestines. Subsequent studies revealed that Rab18 has a wide intracellular distribution; localising to the is_associated_with::Golgi complex, is_associated_with::endoplasmic reticulum, lipid droplets, and is_associated_with::cytosol of various cell types. In the brain, Rab18 has been isolated in association with is_associated_with::synaptic vesicles and has been observed to localise to secretory granules in neuroendocrine cells.