SNAPAP

SNARE-associated protein Snapin is a is_associated_with::protein that in humans is encoded by the SNAPIN is_associated_with::gene.

Interactions
SNAPAP has been shown to interact with is_associated_with::SNAP-25, is_associated_with::BLOC1S1, is_associated_with::SNAP23, is_associated_with::Dysbindin, is_associated_with::TRPV1, is_associated_with::PLDN, is_associated_with::BLOC1S2 and is_associated_with::RGS7.

Function
Snapin has been established to be a promoter of vesicle docking, as it plays a role in binding to is_associated_with::SNAP-25, which together stabilize and favor SNARE complex assembly and vesicle docking. Specifically, the degree to which snapin is necessary for proper synaptic release varies across species. The functions of snapin have been reported to be independent of is_associated_with::synaptotagmin, and works through the is_associated_with::SNAP-25 pathway to stabilize, prime, and dock vesicles.