Rs80356682

rs80356682, also known as R635X, is a SNP in the laminin, beta 3 LAMB3 gene. This SNP is termed i5012672 by 23andMe.

The rare rs80356682(T) allele is a mutation associated with epidermolysis bullosa when co-inherited with another LAMB3 mutation.

According to 23andMe, this SNP is relatively common, accounting for at least 30% of all Herlitz JEB-causing mutations, and it has been reported in individuals of European ancestry from many locations.