Prostaglandin D2 synthase

Prostaglandin-H2 D-isomerase (PTGDS) is an is_associated_with::enzyme that in humans is encoded by the PTGDS is_associated_with::gene.

Furthermore, PTGDS and its product PGD2 are elevated in the bald-scalp areas of men with male pattern baldness (is_associated_with::androgenetic alopecia).

Clinical use
Prostaglandin D2 synthase is used clinically as a diagnostic marker for is_associated_with::liquorrhea, that is, to check whether fluid leaking from the nose or ear contains is_associated_with::cerebrospinal fluid. This is important in the assessment of is_associated_with::head trauma severity. In a medical context, the older term "β-trace protein" is frequently used to refer to PTGDS.