HK2

Hexokinase 2 also known as HK2 is an is_associated_with::enzyme which in humans is encoded by the HK2 is_associated_with::gene.

Function
is_associated_with::Hexokinases phosphorylate is_associated_with::glucose to produce is_associated_with::glucose 6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of is_associated_with::mitochondria. Expression of this gene is is_associated_with::insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.