Category:Interleukin-7 receptor alpha deficiency

A severe combined immunodeficiency that results from defective IL7R expression causes T-B+NK+ SCID. Loss of IL-7R function leads to the loss of an antiapoptotic signal, resulting in a loss of T-cell selection in thymus.

equivalent URI:=http://purl.obolibrary.org/obo/DOID_0060015