HMOX2

Heme oxygenase 2 is an is_associated_with::enzyme that in humans is encoded by the HMOX2 is_associated_with::gene.

Function
is_associated_with::Heme oxygenase, an essential enzyme in is_associated_with::heme catabolism, cleaves heme to form is_associated_with::biliverdin, which is subsequently converted to bilirubin by is_associated_with::biliverdin reductase, and is_associated_with::carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 is_associated_with::isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. is_associated_with::HMOX1 and HMOX2 (this enzyme) belong to the heme oxygenase family.