Rs689465

rs689465 is a SNP in the PTGS2 gene, also known as COX-2, that has been associated with increased risk for mild asthma based on a study of 663 Australian patients. The odds ratio for mild asthma associated with (A;A) genotypes was 1.5 (CI: 1.12-2.02, p=0.02).

Pyrosequencing of polymorphisms in the COX-2 gene (PTGS2) with reported clinical relevance.

Cyclooxygenase-2 polymorphisms and susceptibility to esophageal cancer: a meta-analysis.

Interaction of cyclooxygenase-2 promoter polymorphisms with Helicobacter pylori infection and risk of gastric cancer.

Functional genetic variations of cyclooxygenase-2 and susceptibility to acute myeloid leukemia in a Chinese population.

Polymorphisms in cycloxygenase-2 gene and breast cancer prognosis: association between PTGS2 haplotypes and histopathological features.


 * is_associated_with_disease::Esophageal cancer
 * is_associated_with_disease::Asthma
 * is_associated_with_disease::Acute myeloid leukemia
 * is_associated_with_disease::Breast cancer