CASP8AP2

CASP8-associated protein 2 is a is_associated_with::protein that in humans is encoded by the CASP8AP2 is_associated_with::gene.

Function
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis.

Interactions
CASP8AP2 has been shown to interact with is_associated_with::TRAF2.