Rs121912763

rs121912763 is a polymorphism in the RHD gene known as weak Rh D, and formerly known as D(u).

A total of 16 different molecular weak D types plus 2 alleles characteristic of partial D have been identified. Most, if not all, weak D phenotypes carry altered RhD proteins, suggesting a causal relationship. Genotyping of weak D may guide Rhesus-negative transfusion policy for such molecular weak D types that were prone to develop anti-D, and who risk transfusion reactions if transfused with Rh D positive blood.