Thymidylate synthase inhibitor

Thymidylate synthase inhibitors are chemical agents which inhibit the enzyme Thymidylate synthase and have potential as an anticancer chemotherapy.

Examples
In 2002 five were in clinical trials: raltitrexed, pemetrexed, nolatrexed, ZD9331, and GS7904L.

Examples include
 * Raltitrexed used for colorectal cancer since 1998


 * fluorouracil used for colorectal cancer


 * BGC 945