EGOT (gene)

EGOT, also known as is_associated_with::Eosinophil Granule is_associated_with::Ontogeny (EGO)† Transcript (non-protein coding), is a is_associated_with::human is_associated_with::gene at 3p26.1 encoding a is_associated_with::long noncoding RNA molecule. EGOT is nested within an is_associated_with::intron of the inositol triphosphate receptor type 1 (is_associated_with::ITPR1) gene. The EGOT transcript is expressed during eosinophil development and is possibly involved in regulating eosinophil granule protein expression. Comparison of EGO-B, the spliced isoform, suggests EGOT may be conserved across placental mammals.

†Originally published as EGO but renamed as EGOT because 'EGO' is a real word and is therefore problematic when searching the scientific literature.