ALS2CR8

Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein also known as calcium-response factor (CaRF) is a is_associated_with::protein that in humans is encoded by the ALS2CR8 is_associated_with::gene.

Knocking out the Carf (Als2cr8) gene in mice results in learning associated deficits. Furthermore Carf has been shown to function as a is_associated_with::transcription factor that regulates the expression of BDNF.