AP1S2

AP-1 complex subunit sigma-2 is a is_associated_with::protein that in humans is encoded by the AP1S2 is_associated_with::gene.

Function
Adaptor protein complex 1 is found at the is_associated_with::cytoplasmic face of coated vesicles located at the is_associated_with::Golgi complex, where it mediates both the recruitment of is_associated_with::clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small is_associated_with::adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants utilizing alternative is_associated_with::polyadenylation signals exist for this gene.