Cartilage associated protein

Cartilage associated protein is a is_associated_with::protein that in humans is encoded by the CRTAP is_associated_with::gene.

Function
The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/is_associated_with::ARNO family in response to specific cellular stimuli.

Clinical significance
Mutations in the CRTAP gene are associated with is_associated_with::osteogenesis imperfecta, types VII and IIB, a connective tissue disorder characterized by bone fragility and low bone mass.