AZGP1

Zinc-alpha-2-glycoprotein is a is_associated_with::protein that in humans is encoded by the AZGP1 is_associated_with::gene.

This gene expresses a soluble is_associated_with::protein that stimulates is_associated_with::lipolysis, induces a reduction in is_associated_with::body fat in mice, is associated with the is_associated_with::cachexia related to is_associated_with::cancer, and is known to be expressed in secretory cells of is_associated_with::lung is_associated_with::epithelium. In 2009, it was found that is_associated_with::smoking increases expression of this gene, which is why is_associated_with::smoking cessation leads to weight gain. Zinc-alpha-2-glycoprotein levels also rise with onset of Diabetes 2, which accounts for weight loss thereafter.