FBXL3

F-box/LRR-repeat protein 3 is a is_associated_with::protein that in humans is encoded by the FBXL3 is_associated_with::gene.

Function
This gene encodes a member of the is_associated_with::F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in is_associated_with::phosphorylation-dependent is_associated_with::ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing is_associated_with::WD40 repeats, Fbls containing is_associated_with::leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.

Interactions
FBXL3 has been shown to interact with is_associated_with::SKP1A.