Chronic myelomonocytic leukemia

Chronic myelomonocytic leukemia (CMML) is a form of leukemia featuring monocytosis.

The categorization of this disease has been controversial. Patients with CMML can present with various different clinical features, mimicking either myelodysplastic syndroms or myeloproliferative neoplasms depending upon a patient's specific presentation. Due to this controversy it was classified by the World Health Organization in a "myelodysplastic/myeloproliferative" category of medical conditions in the early 2000s.

Some clinicians distinguish between myelodysplastic and myeloproliferative forms of CMML.