Entactin

Entactin also known as nidogen-1 (NID-1) is a is_associated_with::protein that in humans is encoded by the NID1 is_associated_with::gene. Entactin is a component of the is_associated_with::basement membrane alongside other components such as is_associated_with::collagen type IV, is_associated_with::proteoglycans (heparan sulfate and glycosaminoglycans), is_associated_with::laminin and is_associated_with::fibronectin.

Function
Entactin is a member of the nidogen family of is_associated_with::basement membrane glycoproteins. The protein interacts with several other components of basement membranes. Structurally it (along with is_associated_with::perlecan) connects the networks formed by is_associated_with::collagens and is_associated_with::laminins to each other. It may also play a role in cell interactions with the is_associated_with::extracellular matrix.

Interactions
Entactin has been shown to interact with is_associated_with::FBLN1.