CCDC8

Coiled-coil domain containing 8 is a is_associated_with::protein that in humans is encoded by the CCDC8 is_associated_with::gene.

Function
This gene encodes a is_associated_with::coiled coil domain-containing protein. The encoded protein functions as a cofactor required for is_associated_with::p53-mediated is_associated_with::apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1.

Clinical relevance
Mutations in this gene have been shown to cause is_associated_with::3-M syndrome.