SLC30A3

Zinc transporter 3 also known as solute carrier family 30 member 3 is a is_associated_with::protein in humans that is encoded by the SLC30A3 is_associated_with::gene.

The SLC30A3 gene codes for the ZnT-3 SLC30A family membrane transport protein. ZnT-3 is required for the accumulation of is_associated_with::zinc ions inside is_associated_with::synaptic vesicles. In mice, ZnT-3 is required for some forms of memory that depend on the is_associated_with::hippocampus and the is_associated_with::amygdala. Zinc transport by ZnT-3 modulates memory formation by acting through the is_associated_with::extracellular signal-regulated kinases signaling pathway. is_associated_with::Angiotensin II-induced senescence of vascular smooth muscle cells requires down-regulation of ZnT-3 and ZnT-10.