FKBP3

FK506-binding protein 3 is a is_associated_with::protein that in humans is encoded by the FKBP3 is_associated_with::gene.

Function
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

Interactions
FKBP3 has been shown to interact with is_associated_with::YY1, is_associated_with::HDAC1, is_associated_with::Histone deacetylase 2 and is_associated_with::Mdm2.