Fezolamine

Fezolamine (Win-41,528-2) is a drug which was investigated as an antidepressant in the 1980s. It acts as a serotonin, norepinephrine, and dopamine reuptake inhibitor, with 3- to 4-fold preference for the former neurotransmitter. It was found to be effective and well-tolerated in clinical trials but was never marketed.