Ifosfamide

Ifosfamide (pronounced eye.fos'.fa.mide) (also marketed as Mitoxana and Ifex) is a nitrogen mustard alkylating agent used in the treatment of cancer.

It is sometimes abbreviated "IFO".

Uses
It is given as a treatment for a variety of cancers, including:


 * Testicular cancer
 * Breast cancer
 * Lymphoma (Hodgkin's and Non-Hodgkin's)
 * Soft tissue sarcoma
 * Osteogenic sarcoma (Bone cancer)
 * Lung cancer
 * Cervical cancer
 * Ovarian cancer

Administration
It is a white powder which, when prepared for use in chemotherapy becomes a clear, colorless fluid. The delivery is intravenous.

Ifosfamide is often used in conjunction with Mesna to avoid internal bleeding in the patient, in particular hemorrhagic cystitis.

Ifosfamide is given quickly, and in some cases can be given in as little as an hour.