MYF6

Myogenic factor 6 (herculin) is a is_associated_with::protein that in humans is encoded by the MYF6 is_associated_with::gene. Also known in the medical literature as MRF4 and herculin), MYF6 is a is_associated_with::myogenic regulatory factor (MRF) in the process known as is_associated_with::myogenesis.

Function
MYF6 is a member of the myogenic factors (MYF) family that regulate is_associated_with::myogenesis and muscle regeneration. Myogenic factor are is_associated_with::basic helix-loop-helix (bHLH) is_associated_with::transcription factors. Defects in this gene are a cause of autosomal dominant is_associated_with::centronuclear myopathy (ADCNM).

Clinical significance
Mutations in the MYF6 gene are associated with is_associated_with::myopathy.