DLL3

Delta-like 3 (Drosophila), also known as DLL3, is a is_associated_with::protein which in humans is encoded by the DLL3 is_associated_with::gene. Two transcript variants encoding distinct isoforms have been identified for this gene.

Function
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.

Clinical significance
Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1.