RNF213

Ring finger protein 213 is a is_associated_with::protein that in humans is encoded by the RNF213 is_associated_with::gene.

Clinical relevance
A genome-wide association study identified RNF213 as the first gene associated to is_associated_with::Moyamoya disease. Given that oxygen and glucose consumption scales with total neuron number, RNF213 may have played a role in facilitating the evolution of larger brains in primates.