TP53BP1

Tumor suppressor p53-binding protein 1 also known as p53-binding protein 1 or 53BP1 is a is_associated_with::protein that in humans is encoded by the TP53BP1 is_associated_with::gene.

Clinical significance
53BP1 is underexpressed in most cases of is_associated_with::triple-negative breast cancer.

Interactions
53BP1 has been shown to interact with is_associated_with::Histone H4 dimethylated or monomethylated at Lysine 20, is_associated_with::Replication protein A1, is_associated_with::RPA2, is_associated_with::E2F1, is_associated_with::Ataxia telangiectasia mutated, is_associated_with::p53,       is_associated_with::PAXIP1,  is_associated_with::DYNLL1, is_associated_with::H2AFX   and is_associated_with::Bloom syndrome protein.