SART3

Squamous cell carcinoma antigen recognized by T-cells 3 is a is_associated_with::protein that in humans is encoded by the SART3 is_associated_with::gene.

The is_associated_with::protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection is_associated_with::antigen. This antigen possesses tumor is_associated_with::epitopes capable of inducing is_associated_with::HLA-A24-restricted and tumor-specific cytotoxic is_associated_with::T lymphocytes in cancer patients and may be useful for specific is_associated_with::immunotherapy. This gene product is found to be an important cellular factor for is_associated_with::HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 is_associated_with::snRNPs during the recycling phase of the is_associated_with::spliceosome cycle. This encoded protein is thought to be involved in the regulation of is_associated_with::mRNA splicing.

Interactions
SART3 has been shown to interact with is_associated_with::RNPS1 and is_associated_with::Androgen receptor.