DTNB

Beta dystrobrevin also known as DTNB is a is_associated_with::protein which in humans is encoded by the DTNB is_associated_with::gene.

Function
This gene encodes dystrobrevin beta, a component of the is_associated_with::dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including is_associated_with::dystroglycans, is_associated_with::sarcoglycans, is_associated_with::syntrophins and is_associated_with::dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.