CEP192

Centrosomal protein of 192 kDa, also known as Cep192, is a is_associated_with::protein that in humans is encoded by the CEP192 is_associated_with::gene. It is the homolog of the C. elegans and D. melanogaster gene SPD-2.

Cep192 is a major regulator of is_associated_with::pericentriolar material recruitment, is_associated_with::centrosome maturation, and is_associated_with::centriole duplication in is_associated_with::mammalian cells. It stimulates the formation of the scaffolding upon which is_associated_with::gamma tubulin ring complexes and other proteins involved in is_associated_with::microtubule nucleation and spindle assembly become functional during is_associated_with::mitosis.