HNF1A

HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A, is a human is_associated_with::gene.

The is_associated_with::protein encoded by this gene is a is_associated_with::transcription factor that is highly expressed in the liver and is involved in the regulation of the expression of several liver-specific genes.

Clinical significance
HNF1A mutations can cause maturity onset diabetes of the young type 3, one of the forms of "monogenic diabetes", as well as is_associated_with::hepatocellular adenoma.

Interactions
HNF1A has been shown to interact with:
 * is_associated_with::CREB-binding protein and
 * is_associated_with::EP300,
 * is_associated_with::PCAF,
 * is_associated_with::PCBD1,
 * is_associated_with::RAC3, and
 * Src.