AMFR

Autocrine motility factor receptor, isoform 2 is a is_associated_with::protein that in humans is encoded by the AMFR is_associated_with::gene.

Model organisms
is_associated_with::Model organisms have been used in the study of AMFR function. A conditional is_associated_with::knockout mouse line, called Amfrtm1a(KOMP)Wtsi was generated as part of the is_associated_with::International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.

Male and female animals underwent a standardized is_associated_with::phenotypic screen to determine the effects of deletion. Twenty six tests were carried out on is_associated_with::mutant mice and one significant abnormality was observed: Fewer than expected homozygous mutant mice survived until is_associated_with::weaning.

Interactions
AMFR has been shown to interact with is_associated_with::Valosin-containing protein.