ARL13B

ADP-ribosylation factor-like protein 13B (ARL13B), also known as ADP-ribosylation factor-like protein 2-like 1, is a is_associated_with::protein that in humans is encoded by the ARL13B is_associated_with::gene.

Function
This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small is_associated_with::GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the is_associated_with::cilia and plays a role in cilia formation and in maintenance of cilia.

Clinical significance
Mutations in the ARL13B gene are associated with the is_associated_with::Joubert syndrome.