RAG1

Recombination activating gene 1 also known as RAG-1 is a is_associated_with::protein that in humans is encoded by the RAG1 is_associated_with::gene.

The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires is_associated_with::RAG2. Defects in this gene can be the cause of several diseases.