Rs41313031

rs41313031, also known as Leu1308Phe or L1308F, is a SNP in the cardiac sodium channel SCN5A gene.

Some individuals carry two mutations on the same (gene) allele, consisting of rs45471994(A) and rs41313031(A). When exposed to lidocaine, these "double mutant" individuals may develop ventricular tachycardia consistent with Brugada syndrome.