LRRC50

Leucine-rich repeat-containing protein 50 is a is_associated_with::protein that in humans is encoded by the LRRC50 is_associated_with::gene.

Function
Leucine-rich repeat-containing protein 50 is is_associated_with::cilium-specific and is required for the stability of the ciliary architecture. It is involved in the regulation of is_associated_with::microtubule-based cilia and actin-based brush border is_associated_with::microvilli.

Clinical significance
Mutations in the LRRC50 gene are associated with is_associated_with::primary ciliary dyskinesia.