FAM18B1

Family with sequence similarity 18 member B1 (FAM18B1) is the hypothetical is_associated_with::protein encoded by the is_associated_with::gene LOC51030. Evidence for this protein only exists at the transcript level. The gene is found on is_associated_with::chromosome 17 on the cytogenetic band 17p11.2.

This gene has one is_associated_with::paralog in the human is_associated_with::genome, LOC201158, which is located on chromosome 17 at 17p12. The duplication appears to have appeared after the MRCA of humans and apes. This gene has homologs in eukaryotes as far back as is_associated_with::Trichoplax.

Gene
LOC51030 is highly conserved in is_associated_with::chordates and also shows conservation in is_associated_with::eukaryotes, including fungi and plants. It is located on Chromosome 17 at 18,684,582-18,710,026, and the most common mRNA has 7 is_associated_with::exons.

Protein
This gene encode a protein of 205 is_associated_with::amino acids in length and a predicted molecular weight of 23.57 kDa. This protein is predicted to have an is_associated_with::isoelectric point of 8.62. It contains a is_associated_with::domain of unknown function, DUF846, and a predicted phosphoserine site. It is a multipass is_associated_with::transmembrane protein and a member of the FAM18/TVP23 superfamily.

FAM18B1 appears to be ubiquitously expressed in all tissues, health states, and developmental stages to some level. There is also notable expression in bladder tissue.